PIK3CA Mutations Frequently Coexist with RAS and BRAF Mutations in Patients with Advanced Cancers

RT @4baseCare: Oncogenic mutations of PIK3CA, RAS (KRAS, NRAS), and BRAF have been identified in various malignancies, and activate the PI3…

Oncogenic mutations of PIK3CA, RAS (KRAS, NRAS), and BRAF have been identified in various malignancies, and activate the PI3K/AKT/mTOR and RAS/RAF/MEK pathways, respectively. LINK: https://t.co/uuNfg7WL2X #MedTwitter https://t.co/bkcYXHBKOy

@MasonIsraelPhD @VasanNeil Pardon my ignorance. Picking #twitterverse🧠. 🧬PIK3CA is☝🏽gene that I’m still learning about. So it does go ↪️the route of PI3KCA-AKT-MTOR but also ↩️➕RAS/RAF. In #CRCSM we see comutations. If PIK3CA➕KRAS mutant, who is the dr