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Intravenous transplantation of mesenchymal stem cells preconditioned with early phase stroke serum: current evidence and study protocol for a randomized trial

Overview of attention for article published in Trials, October 2013
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Title
Intravenous transplantation of mesenchymal stem cells preconditioned with early phase stroke serum: current evidence and study protocol for a randomized trial
Published in
Trials, October 2013
DOI 10.1186/1745-6215-14-317
Pubmed ID
Authors

Suk Jae Kim, Gyeong Joon Moon, Won Hyuk Chang, Yun-Hee Kim, Oh Young Bang, For the STARTING-2 (STem cell Application Researches and Trials In NeuroloGy-2) collaborators

Abstract

Recovery after a major stroke is usually limited, but cell therapy for patients with fixed neurologic deficits is emerging. Several recent clinical trials have investigated mesenchymal stem cell (MSC) therapy for patients with ischemic stroke. We previously reported the results of a controlled trial on the application of autologous MSCs in patients with ischemic stroke with a long-term follow-up of up to 5 years (the 'STem cell Application Researches and Trials In NeuroloGy' (STARTING) study). The results from this pilot trial are challenging, but also raise important issues. In addition, there have been recent efforts to improve the safety and efficacy of MSC therapy for stroke.

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Mendeley readers

The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Japan 1 <1%
United States 1 <1%
Unknown 127 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 17%
Student > Bachelor 20 15%
Student > Postgraduate 14 11%
Student > Ph. D. Student 13 10%
Student > Master 11 8%
Other 22 17%
Unknown 29 22%
Readers by discipline Count As %
Medicine and Dentistry 38 29%
Agricultural and Biological Sciences 18 14%
Neuroscience 10 8%
Biochemistry, Genetics and Molecular Biology 9 7%
Nursing and Health Professions 3 2%
Other 19 15%
Unknown 34 26%