As per the paper 'Guidelines for Validation of Next-Generation Sequencing Based Oncology Panel' (https://t.co/ZFVxvi3ufL) the depth of coverage is 250X . Is there any update on the recommended depth of coverage from 250X for Hybridization capture sequencin
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To be 95% confident you will be 95% correct in each sample (we are sampling a population with unknown parameters and many sources of uncertainty), Jenning et al says to apply the rule of 3. (Based on the natural log of 0.05). You need 60 cases! (2/2) https
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Jennings et al. ("Guidelines for Validation of Next-Generation Sequencing-Based Oncology Panels"; https://t.co/0TbnRDFC2P) providing salient, comprehensive guidelines for the design and implementation of oncology gene panels. Equally valid for most gene p
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RT @JMDiagn: The guideline is free to all readers online here: https://t.co/XQmdNyQY0i #AMPEurope2018 https://t.co/pxNcBByb76