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8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications

Overview of attention for article published in Drug Design, Development and Therapy, October 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

twitter
1 X user
patent
4 patents
video
1 YouTube creator

Citations

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332 Dimensions

Readers on

mendeley
358 Mendeley
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Title
8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications
Published in
Drug Design, Development and Therapy, October 2013
DOI 10.2147/dddt.s49763
Pubmed ID
Authors

Veda Prachayasittikul, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul

Abstract

Metal ions play an important role in biological processes and in metal homeostasis. Metal imbalance is the leading cause for many neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 8-Hydroxyquinoline (8HQ) is a small planar molecule with a lipophilic effect and a metal chelating ability. As a result, 8HQ and its derivatives hold medicinal properties such as antineurodegenerative, anticancer, antioxidant, antimicrobial, anti-inflammatory, and antidiabetic activities. Herein, diverse bioactivities of 8HQ and newly synthesized 8HQ-based compounds are discussed together with their mechanisms of actions and structure-activity relationships.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 358 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 <1%
Germany 1 <1%
Bulgaria 1 <1%
Australia 1 <1%
Sweden 1 <1%
United States 1 <1%
Poland 1 <1%
Unknown 350 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 68 19%
Researcher 43 12%
Student > Master 42 12%
Student > Bachelor 34 9%
Other 15 4%
Other 56 16%
Unknown 100 28%
Readers by discipline Count As %
Chemistry 106 30%
Biochemistry, Genetics and Molecular Biology 35 10%
Agricultural and Biological Sciences 28 8%
Medicine and Dentistry 16 4%
Pharmacology, Toxicology and Pharmaceutical Science 16 4%
Other 48 13%
Unknown 109 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2021.
All research outputs
#7,968,340
of 25,394,764 outputs
Outputs from Drug Design, Development and Therapy
#543
of 2,270 outputs
Outputs of similar age
#67,976
of 219,927 outputs
Outputs of similar age from Drug Design, Development and Therapy
#11
of 39 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 2,270 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 219,927 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.