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Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing

Overview of attention for article published in Epigenetics & Chromatin, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#40 of 351)
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

blogs
1 blog
twitter
10 tweeters

Readers on

mendeley
98 Mendeley
citeulike
1 CiteULike
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Title
Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing
Published in
Epigenetics & Chromatin, January 2013
DOI 10.1186/1756-8935-6-33
Pubmed ID
Authors

Dustin R Masser, Arthur S Berg, Willard M Freeman

Abstract

The growing interest in the role of epigenetic modifications in human health and disease has led to the development of next-generation sequencing methods for whole genome analysis of DNA methylation patterns. However, many projects require targeted methylation analysis of specific genes or genomic regions. We have developed an approach, termed BiSulfite Amplicon Sequencing (BSAS), for hypothesis driven and focused absolute DNA methylation analysis. This approach is applicable both to targeted DNA methylation studies as well as to confirmation of genome-wide studies.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
India 1 1%
Unknown 95 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 27 28%
Student > Ph. D. Student 20 20%
Student > Master 9 9%
Professor > Associate Professor 9 9%
Student > Bachelor 7 7%
Other 20 20%
Unknown 6 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 38%
Biochemistry, Genetics and Molecular Biology 28 29%
Medicine and Dentistry 9 9%
Neuroscience 6 6%
Engineering 3 3%
Other 7 7%
Unknown 8 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2014.
All research outputs
#976,692
of 12,378,406 outputs
Outputs from Epigenetics & Chromatin
#40
of 351 outputs
Outputs of similar age
#14,923
of 166,793 outputs
Outputs of similar age from Epigenetics & Chromatin
#2
of 11 outputs
Altmetric has tracked 12,378,406 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 351 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,793 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.