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Leishmaniasis

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Cover of 'Leishmaniasis'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Aetiology and Epidemiology: Overview
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    Chapter 2 The Genus Leishmania in the Middle East and USSR
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    Chapter 3 Epidemiology of Mediterranean Leishmaniasis Caused by Leishmania Infantum: Isoenzyme and kDna Analysis for The Identification of Parasites from Man, Vectors and Reservoirs
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    Chapter 4 Leishmaniasis: Status in Tunisia (1986)
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    Chapter 5 A Review of the Status of Leishmaniasis in Pakistan from 1960 – 1986
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    Chapter 6 Zoonoses and Leishmaniasis
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    Chapter 7 Reservoirs of Visceral Leishmaniasis
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    Chapter 8 Effectiveness of Control Measures Against Canine Leishmaniasis in the Isle of Elba, Italy
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    Chapter 9 The Incidence of Canine Leishmaniasis in Northern Greece: An Epizootiological Study of the Decade 1977–1987
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    Chapter 10 Studies on the Role of the Ground Squirrel (Citellus Citellus): In the Epidemiology of Leishmaniasis
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    Chapter 11 Field Application of A Direct Agglutination Test for Visceral Leishmaniasis
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    Chapter 12 Leishmaniasis in the Lowlands of Bolivia (Leishbol) Part I . An Overview of the Integrated Project for the Characterization, Vigilance and Control of Leishmaniasis
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    Chapter 13 Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part II. Community Health Care for Spontaneous Settlers in Endemictropical Forest
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    Chapter 14 Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part III. Status of the Disease in an Area of Spontaneous Agricultural Colonization
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    Chapter 15 Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part IV. Field Identification Key for Lutzomya SPP. Based on Thoracic External Characters
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    Chapter 16 Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part V. Monthly Density of Lutzomya Yucumensis, Lu. Davisi and Lu. Carrerai carrerai in the Rain Forest of Yapacani, Department of Santa Cruz
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    Chapter 17 Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part VI. Flagellate Infection in Sandflies from the Rain Forest of Yapacani
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    Chapter 18 Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part VII. Preliminary Characterization of Eleven Leishmania Isolates
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    Chapter 19 Leishmaniasis in the Lowlawnds of Bolivia (Leishbol): Part VIII. Characterization and Identification of Bolivian Isolates by PFG Karyotyping
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    Chapter 20 The Distribution and Aetiology of Diffuse Cutaneous Leishmaniasis in the New World
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    Chapter 21 Epidemiological Studies on Cutaneous Leishmaniasis in the State of Rio de Janeiro, Brazil. Domestic and Peridomestic Sandfly Fauna
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    Chapter 22 Evaluation of the Canine Reservoir of Visceral Leishmaniasis: A Methodological Review
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    Chapter 23 The Ecology and Entomology of the Leishmaniases
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    Chapter 24 Sandfly Breeding Sites
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    Chapter 25 Leishmaniasis Research in Kenya: Parasite-Vector-Host Associations
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    Chapter 26 Sandflies and Disease in Cyprus; 1944 – 1985
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    Chapter 27 The Effect of Permethrin Impregnated Nets on Phlebotomus (Diptera: Psychodidae) in Central Italy
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    Chapter 28 Cuticular Hydrocarbon Analysis as a Tool in Sandfly Identification
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    Chapter 29 Bioassays as an Indicator of Pheromone Communication in Lutzomyia Longipalpis (Diptera: Psychodidae)
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    Chapter 30 Why Measure the Vectorial Capacity of Sandflies?
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    Chapter 31 Cell Biology and Immunology of Leishmaniasis
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    Chapter 32 Studies of Immune Mechanisms in H-11-Linked Genetic Susceptibility to Murine Visceral Leishmaniasis
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    Chapter 33 Characterization of Leishmania Donovani Infective (Metacyclic) Promastigotes from Axenic Cultures
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    Chapter 34 Different Epitopes of the Macrophage Type Three Complement Receptor (CR3) Are Used to Bind Leishmania Promastigotes Harvested at Different Phases of Their Growth Cycle
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    Chapter 35 Immunodominant Epitopes of the Leishmania Surface Membrane
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    Chapter 36 Antigens Recognized by Sera from Patients with Visceral Leishmaniasis
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    Chapter 37 Interactions Between Leishmaniasis and Malaria
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    Chapter 38 Modulation of Cell-Mediated Immunity in Experimental Cutaneous Leishmaniasis
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    Chapter 39 The Local T Cell Response in Experimental Leishmaniasis
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    Chapter 40 The Role of Specific T Cell Subsets in the Immunological Control of Experimental Cutaneous Leishmaniasis
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    Chapter 41 Parameters of T Cell Activation in Murine Leishmaniasis
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    Chapter 42 A Possible Role for Prostaglandins in Regulation of Disease in Murine Cutaneous Leishmaniasis
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    Chapter 43 Use of a Dot-Elisa Procedure for the Detection of Specific Antibodies in Cutaneous Leishmaniasis
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    Chapter 44 A Novel Method of Vaccination Using Parasite Membrane Antigens
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    Chapter 45 Leishmania Major: Immune Responses Elicited by Carbohydrate-Lipid Containing Fractions (CLF)
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    Chapter 46 Premunition, A Possible Limitation in the Prevention of the Leishmaniases by Vaccination
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    Chapter 47 Immunological Profiles in Indian Post Kala-Azar Dermal Leishmaniasis
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    Chapter 48 Evaluation of Non-Specific Immunity in Canine Leishmaniasis
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    Chapter 49 Variation in Leishmania Species Expressed by Antigenic Glycoconjugates and Excreted Factor
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    Chapter 50 Preliminary Studies on the Detection of Circulating Antigen in Visceral Leishmaniasis
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    Chapter 51 The 63kDa Promastigote Protease of Lesihmania: Assessment of Host-Protection in Balb/C Mice using Liposomes as Adjuvant
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    Chapter 52 Studies on Antigenicity of Amphiphilic and Hydrophilic Forms of Leishmania Major Promastigote Surface Protease in the Mouse
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    Chapter 53 Histopathogenic Mechanisms in American Cutaneous Leishmaniasis of Mice
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    Chapter 54 The Role of Membrane-Stabilizing Drugs on Uptake of Leishmania Parasites by Human Macrophages
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    Chapter 55 Generation of Megasomes During the Promastigote — Amastigote Transformation of Leishmania Mexicana Mexicana in Vitro
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    Chapter 56 Treatment of Experimental Cutaneous and Visceral Murine Leishmaniasis with Recombinant Gamma-Interferon
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    Chapter 57 Molecular Biology and Biochemistry: An Overview
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    Chapter 58 Biochemical Mechanisms of Pentostam
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    Chapter 59 EFFECTS OF SINEFUNGIN ON CELLULAR AND BIOCHEMICAL EVENTS IN PROMASTIGOTES OF LEISHMANIA d. donovani
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    Chapter 60 Metabolism and Functions of Trypanothione with Special Reference to Leishmaniasis
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    Chapter 61 The Sterols of Leishmania Promastigotes and Amastigotes: Possible Implications for Chemotherapy
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    Chapter 62 Assessment of the Use in the Diagnosis of Leishmaniasis of Biotinylated Kinetoplast Derived DNA Sequences
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    Chapter 63 Application of Total and Recombinant DNA Probes in the Diagnosis of Leishmania Infections
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    Chapter 64 BIOTINYLATED kDNA FROM Leishmania braziliensis
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    Chapter 65 Karyotype Analysis of Leishmania Donovani
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    Chapter 66 Abnormally Migrating Chromosome Identifies Leishmania Donovani Populations
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    Chapter 67 Kinetoplast DNA Probes for the Identification of the Old World Cutaneous Leishmaniases
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    Chapter 68 Small Nucleic Acids in Leishmania
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    Chapter 69 Gene Expression in the Infective Promastigotes of Leishmania Major
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    Chapter 70 In Vitro and in Vivo Differentiation of L.Mexicana-Hsp70 Gene Expression
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    Chapter 71 Thermoregulated Antigen Expression by Leishmania Promastigotes
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    Chapter 72 A Simple, Highly Repetitive Sequence in the Leishmania Genome
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    Chapter 73 Cloning and Characterisation of Leishmania Donovani Genes Coding for Immunodominant Antigens
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    Chapter 74 Surface Antigens of Leishmania Infantum Identified by Monoclonal Antibodies: Isolation of a Monomeric and an Oligomeric form of a Major L. Infantum Antigen
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    Chapter 75 Sequence Analysis of the Major Surface Glycoprotein of Leishmania Major
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    Chapter 76 Structure Function Studies on Leishmania Surface Membrane Proteins
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    Chapter 77 The Promastigote Surface Protease of Leishmania: pH Optimum and Effects of Protease Inhibitors
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    Chapter 78 Proteolysis in Leishmania: Species Differences and Developmental Changes in Proteinase Activity
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    Chapter 79 The Leishmania Donovani Lipophosphoglycan: Structure and Function
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    Chapter 80 Immunochemical Characterization of the Leishmania Donovani 3′-Nucleotidase
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    Chapter 81 Interrelations between Glucose and Alanine Catabolism, Ammonia Production, and the D-Lactate Pathway in Leishmania Braziliensis
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    Chapter 82 Leishmania Amastigotes: Adaptations for Growth in an Acidic in vivo Environment
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    Chapter 83 Abrogation of Skin Lesions in Cutaneous Leishmaniasis by Ultraviolet B Irradiation
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    Chapter 84 Evidence for Hybrid Formation in the Genus Leishmania
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    Chapter 85 Chemotherapy — Overview
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    Chapter 86 The Future for Antileishmanial Chemotherapeutic Agents: A Review
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    Chapter 87 Chemotherapy of Mediterranean Visceral Leishmaniasis with Meglumine Antimoniate
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    Chapter 88 The in vitro Susceptibility of Macrophages Infected with Amastigotes of Leishmania spp. to Pentavalent Antimonial Drugs and Other Compounds with Special Relevance to Cutaneous Isolates
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    Chapter 89 Relapse in Kala Azar: Failure of Sodium Stibogluconate to Clear Parasites from Organs Other than the Liver
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    Chapter 90 From Lysosomes to Cells, From Cells to Leishmania: Amino Acid Esters, Potential Chemotherapeutic Agents?
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    Chapter 91 Antileishmanial Activity of L-Leucine Methyl Ester and L-Tryptophanamide
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    Chapter 92 Inhibition of Leishmania Species by α-Difluoromethylornithine
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    Chapter 93 Antileishmanial Effect of Sinefungin and its Derivatives
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    Chapter 94 Effects of Lanosterol-14α-Demethylation Inhibitors on Propagation and Sterol Biosynthesis of Leishmania Promastigotes and Amastigotes
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    Chapter 95 Effect of Ribosome-Inactivating Proteins on Ribosomes from Leishmania and Their Possible Uses in Chemotherapy
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    Chapter 96 Leishmaniasis-AIDS: Failure to Respond to Chemotherapy
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    Chapter 97 Liposomes and Other Drug Delivery Systems in the Treatment of Leishmaniasis
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    Chapter 98 Carrier Mediated Therapy of Murine Visceral Leishmaniasis
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    Chapter 99 Site Specific Antileishmanial Drug Delivery
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    Chapter 100 New Strategies for Control Forum: Vector Control
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    Chapter 101 Squash Blotting Phlebotomus Papatasi to Estimate Rates of Infection by Leishmania Major
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    Chapter 102 New Strategies for Control Forum: Reservoir Control
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    Chapter 103 New Strategy for Control Forum: Vaccination
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    Chapter 104 Vaccination and the Immunological Control of Leishmaniasis
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    Chapter 105 New Strategies for Control Forum : Chemotherapy
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    Chapter 106 Strategies for the Design of New Antileishmanial Drugs
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    Chapter 107 The Glycosome of Leishmania as a Possible Target for Chemotherapeutic Attack
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    Chapter 108 Molecular Strategies for Antileishmanial Drug Design
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    Chapter 109 Unstable and Stable Gene Amplification in Methotrexate-Resistant Leishmania Major and Natural Isolates of Leishmania Tarentolae
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    Chapter 110 Potential Clinical Use of Sinefungin: Reduction of Toxicity and Enhancement of Activity
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    Chapter 111 Effects of a Squalene-2,3-Epoxidase Inhibitor on Propagation and Sterol Biosynthesis of Leishmania Promastigotes and Amastigotes
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    Chapter 112 Ribosome-Inactivating Proteins and Leishmania: New Strategies for Future Research
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    Chapter 113 Workshop I: Characterisation and Taxonomy of Leishmania
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    Chapter 114 Characterisation by Light Microscope “In Situ” Hybridisation within 12 Hours of Live Leishmania Observation
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    Chapter 115 Enzyme Electrophoretic Evidence for the Importation of L. infantum into the New World
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    Chapter 116 Chromosome Size Homologies im Leishmania Major Determined by Molecular Karyotyping
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    Chapter 117 Identification of Leishmania Tropica by Species Specific Monoclonal Antibodies
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    Chapter 118 Flow Cytometric Analysis of Leishmania Surface Membrane Antigen Expression
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    Chapter 119 On the Clinical Manifestations and Parasites of Old World Leishmaniases and Leishmania Tropica Causing Visceral Leishmaniasis
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    Chapter 120 Workshop II: Sandfly Systematics and Genetics
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    Chapter 121 Sandfly Systematics: Epidemiological Requirements and Current Developments
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    Chapter 122 DNA Probes for Vector Taxonomy
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    Chapter 123 DNA Sequence Polymorphisms as Genotypic Markers for Phlebotomine Vectors of Leishmania
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    Chapter 124 Workshop III: Molecular Genetics of Leishmania Development
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    Chapter 125 Transcript Alteration in Leishmania
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    Chapter 126 Circular and Linear Forms of Small Nucleic Acids in Leishmania
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    Chapter 127 Workshop IV: Chemotherapy and the Immune Response
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    Chapter 128 Clearance of L. Donovani from the Liver of Balb/c Mice Results in Local Resistance to Re-Infection
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    Chapter 129 I — The Field Trip
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    Chapter 130 II — Feral Reservoirs of Leishmaniasis on the Island of Zakinthos
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    Chapter 131 III — Epidemiology of Human and Canine Leishmaniasis on the Island of Zakinthos
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    Chapter 132 Photographs
  134. Altmetric Badge
    Chapter 133 List of Participants
Attention for Chapter 86: The Future for Antileishmanial Chemotherapeutic Agents: A Review
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Chapter title
The Future for Antileishmanial Chemotherapeutic Agents: A Review
Chapter number 86
Book title
Leishmaniasis
Published by
Springer US, January 1989
DOI 10.1007/978-1-4613-1575-9_86
Book ISBNs
978-1-4612-8862-6, 978-1-4613-1575-9
Authors

Jonathan D. Berman

Editors

D. T. Hart

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The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 1 100%
Readers by discipline Count As %
Chemistry 1 100%