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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effect of Iboga Alkaloids on µ-Opioid Receptor-Coupled G Protein Activation
|
|---|---|
| Published in |
PLOS ONE, October 2013
|
| DOI | 10.1371/journal.pone.0077262 |
| Pubmed ID | |
| Authors |
Tamara Antonio, Steven R. Childers, Richard B. Rothman, Christina M. Dersch, Christine King, Martin Kuehne, William G. Bornmann, Amy J. Eshleman, Aaron Janowsky, Eric R. Simon, Maarten E. A. Reith, Kenneth Alper |
| Abstract |
The iboga alkaloids are a class of small molecules defined structurally on the basis of a common ibogamine skeleton, some of which modify opioid withdrawal and drug self-administration in humans and preclinical models. These compounds may represent an innovative approach to neurobiological investigation and development of addiction pharmacotherapy. In particular, the use of the prototypic iboga alkaloid ibogaine for opioid detoxification in humans raises the question of whether its effect is mediated by an opioid agonist action, or if it represents alternative and possibly novel mechanism of action. The aim of this study was to independently replicate and extend evidence regarding the activation of μ-opioid receptor (MOR)-related G proteins by iboga alkaloids. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 27% |
| United Kingdom | 1 | 9% |
| Unknown | 7 | 64% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 55% |
| Scientists | 5 | 45% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 80 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 21% |
| Student > Bachelor | 17 | 21% |
| Student > Master | 11 | 13% |
| Student > Ph. D. Student | 8 | 10% |
| Student > Postgraduate | 4 | 5% |
| Other | 11 | 13% |
| Unknown | 14 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 13% |
| Agricultural and Biological Sciences | 10 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 11% |
| Chemistry | 8 | 10% |
| Psychology | 8 | 10% |
| Other | 19 | 23% |
| Unknown | 17 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 47. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2024.
All research outputs
#877,458
of 25,109,675 outputs
Outputs from PLOS ONE
#11,593
of 217,846 outputs
Outputs of similar age
#7,707
of 217,991 outputs
Outputs of similar age from PLOS ONE
#326
of 5,137 outputs
Altmetric has tracked 25,109,675 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 217,846 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.7. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 217,991 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 5,137 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.