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X Demographics
Mendeley readers
| Title |
Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design
|
|---|---|
| Published in |
Trials, October 2013
|
| DOI | 10.1186/1745-6215-14-335 |
| Pubmed ID | |
| Authors |
Gabriela J Prutsky, Juan Pablo Domecq, Patricia J Erwin, Matthias Briel, Victor M Montori, Elie A Akl, Joerg J Meerpohl, Dirk Bassler, Stefan Schandelmaier, Stephen D Walter, Qi Zhou, Pablo Alonso Coello, Lorenzo Moja, Martin Walter, Kristian Thorlund, Paul Glasziou, Regina Kunz, Ignacio Ferreira-Gonzalez, Jason Busse, Xin Sun, Annette Kristiansen, Benjamin Kasenda, Osama Qasim-Agha, Gennaro Pagano, Hector Pardo-Hernandez, Gerard Urrutia, Mohammad Hassan Murad, Gordon Guyatt |
| Abstract |
Randomized control trials (RCTs) stopped early for benefit (truncated RCTs) are increasingly common and, on average, overestimate the relative magnitude of benefit by approximately 30%. Investigators stop trials early when they consider it is no longer ethical to enroll patients in a control group. The goal of this systematic review is to determine how investigators of ongoing or planned RCTs respond to the publication of a truncated RCT addressing a similar question. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Canada | 1 | 2% |
| Unknown | 41 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 23% |
| Other | 5 | 12% |
| Student > Ph. D. Student | 5 | 12% |
| Professor | 5 | 12% |
| Professor > Associate Professor | 3 | 7% |
| Other | 8 | 19% |
| Unknown | 7 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 56% |
| Economics, Econometrics and Finance | 2 | 5% |
| Unspecified | 1 | 2% |
| Business, Management and Accounting | 1 | 2% |
| Arts and Humanities | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 10 | 23% |