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Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation

Overview of attention for article published in Respiratory Research, October 2013
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Title
Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation
Published in
Respiratory Research, October 2013
DOI 10.1186/1465-9921-14-108
Pubmed ID
Authors

Duane R Winden, Nicholas T Ferguson, Benjamin R Bukey, Alexander J Geyer, Alex J Wright, Zac R Jergensen, Adam B Robinson, Jeffrey A Stogsdill, Paul R Reynolds

Abstract

Receptors for advanced glycation end-products (RAGE) are cell surface receptors prominently expressed by lung epithelium. Previous research demonstrated that over-expression of RAGE by murine alveolar epithelial cells during embryogenesis caused severe lung hypoplasia and neonatal lethality. However, the effects of RAGE over-expression on adjacent matrix and endothelial cells remained unknown.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 24%
Researcher 3 18%
Student > Postgraduate 2 12%
Student > Doctoral Student 1 6%
Student > Ph. D. Student 1 6%
Other 3 18%
Unknown 3 18%
Readers by discipline Count As %
Medicine and Dentistry 6 35%
Biochemistry, Genetics and Molecular Biology 3 18%
Agricultural and Biological Sciences 3 18%
Social Sciences 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Other 0 0%
Unknown 3 18%