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Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities

Overview of attention for article published in Clinical Epigenetics, April 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
6 X users
patent
3 patents

Readers on

mendeley
127 Mendeley
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Title
Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
Published in
Clinical Epigenetics, April 2017
DOI 10.1186/s13148-017-0332-8
Pubmed ID
Authors

Goran Micevic, Nicholas Theodosakis, Marcus Bosenberg

Abstract

Aberrant DNA methylation is an epigenetic hallmark of melanoma, known to play important roles in melanoma formation and progression. Recent advances in genome-wide methylation methods have provided the means to identify differentially methylated genes, methylation signatures, and potential biomarkers. However, despite considerable effort and advances in cataloging methylation changes in melanoma, many questions remain unanswered. The aim of this review is to summarize recent developments, emerging trends, and important unresolved questions in the field of aberrant DNA methylation in melanoma. In addition to reviewing recent developments, we carefully synthesize the findings in an effort to provide a framework for understanding the current state and direction of the field. To facilitate clarity, we divided the review into DNA methylation changes in melanoma, biomarker opportunities, and therapeutic developments. We hope this review contributes to accelerating the utilization of the diagnostic, prognostic, and therapeutic potential of DNA methylation for the benefit of melanoma patients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 <1%
Unknown 126 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 20%
Researcher 17 13%
Student > Master 15 12%
Student > Bachelor 13 10%
Other 9 7%
Other 19 15%
Unknown 29 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 37 29%
Medicine and Dentistry 26 20%
Agricultural and Biological Sciences 12 9%
Immunology and Microbiology 5 4%
Pharmacology, Toxicology and Pharmaceutical Science 4 3%
Other 10 8%
Unknown 33 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2020.
All research outputs
#1,482,652
of 24,654,416 outputs
Outputs from Clinical Epigenetics
#78
of 1,402 outputs
Outputs of similar age
#29,182
of 313,615 outputs
Outputs of similar age from Clinical Epigenetics
#1
of 28 outputs
Altmetric has tracked 24,654,416 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,402 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,615 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.