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Emerging concepts in liquid biopsies

Overview of attention for article published in BMC Medicine, April 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)

Mentioned by

1 news outlet
13 tweeters
1 Facebook page

Readers on

273 Mendeley
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Emerging concepts in liquid biopsies
Published in
BMC Medicine, April 2017
DOI 10.1186/s12916-017-0840-6
Pubmed ID

Samantha Perakis, Michael R. Speicher


Characterizing and monitoring tumor genomes with blood samples could achieve significant improvements in precision medicine. As tumors shed parts of themselves into the circulation, analyses of circulating tumor cells, circulating tumor DNA, and tumor-derived exosomes, often referred to as "liquid biopsies", may enable tumor genome characterization by minimally invasive means. Indeed, multiple studies have described how molecular information about parent tumors can be extracted from these components. Here, we briefly summarize current technologies and then elaborate on emerging novel concepts that may further propel the field. We address normal and detectable mutation levels in the context of our current knowledge regarding the gradual accumulation of mutations during aging and in light of technological limitations. Finally, we discuss whether liquid biopsies are ready to be used in routine clinical practice.

Twitter Demographics

The data shown below were collected from the profiles of 13 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 273 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Denmark 1 <1%
Unknown 270 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 57 21%
Student > Ph. D. Student 53 19%
Student > Master 43 16%
Other 26 10%
Student > Bachelor 24 9%
Other 34 12%
Unknown 36 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 65 24%
Medicine and Dentistry 56 21%
Agricultural and Biological Sciences 52 19%
Engineering 14 5%
Pharmacology, Toxicology and Pharmaceutical Science 12 4%
Other 26 10%
Unknown 48 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2018.
All research outputs
of 12,974,406 outputs
Outputs from BMC Medicine
of 2,070 outputs
Outputs of similar age
of 261,564 outputs
Outputs of similar age from BMC Medicine
of 1 outputs
Altmetric has tracked 12,974,406 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,070 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 34.6. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,564 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them