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Evolution of the human immunodeficiency virus type 2 envelope in the first years of infection is associated with the dynamics of the neutralizing antibody response

Overview of attention for article published in Retrovirology, October 2013
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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3 X users

Citations

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55 Mendeley
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Title
Evolution of the human immunodeficiency virus type 2 envelope in the first years of infection is associated with the dynamics of the neutralizing antibody response
Published in
Retrovirology, October 2013
DOI 10.1186/1742-4690-10-110
Pubmed ID
Authors

Cheila Rocha, Rita Calado, Pedro Borrego, José Maria Marcelino, Inês Bártolo, Lino Rosado, Patrícia Cavaco-Silva, Perpétua Gomes, Carlos Família, Alexandre Quintas, Helena Skar, Thomas Leitner, Helena Barroso, Nuno Taveira

Abstract

Differently from HIV-1, HIV-2 disease progression usually takes decades without antiretroviral therapy and the majority of HIV-2 infected individuals survive as elite controllers with normal CD4⁺ T cell counts and low or undetectable plasma viral load. Neutralizing antibodies (Nabs) are thought to play a central role in HIV-2 evolution and pathogenesis. However, the dynamic of the Nab response and resulting HIV-2 escape during acute infection and their impact in HIV-2 evolution and disease progression remain largely unknown. Our objective was to characterize the Nab response and the molecular and phenotypic evolution of HIV-2 in association with Nab escape in the first years of infection in two children infected at birth.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Portugal 1 2%
Unknown 53 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 22%
Student > Master 8 15%
Student > Ph. D. Student 6 11%
Student > Bachelor 6 11%
Student > Postgraduate 4 7%
Other 11 20%
Unknown 8 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 24%
Medicine and Dentistry 10 18%
Immunology and Microbiology 6 11%
Biochemistry, Genetics and Molecular Biology 4 7%
Chemistry 3 5%
Other 9 16%
Unknown 10 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2013.
All research outputs
#14,118,104
of 22,727,570 outputs
Outputs from Retrovirology
#686
of 1,104 outputs
Outputs of similar age
#118,280
of 211,997 outputs
Outputs of similar age from Retrovirology
#23
of 50 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,104 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,997 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.