Just looked into this further and found a study showing antipsychotics LOWER glutamate in the brain- above study says low glutamate leads to psychosis. Hmmm https://t.co/pZ2Mlp1aGh https://t.co/0WouEIkVn9
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@VernonLab_KCL @JAMAPsych great question! I'm not as up to date with the animal work. Alice references a few here - some studies do find reductions but also varies by type of antipsychotic + animal model https://t.co/WrH8asY3BI
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@Alacoque6 @SameiHuda @JAMAPsych Medication doesn't seem to have much of an effect on MRS measures of glutamate - if anything it may lower levels https://t.co/y7I8Y0w2Kr
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[schizo] Effects of Antipsychotic Administration on Brain Glutamate in Schizophrenia: A Systematic Review of… https://t.co/WbDfdz7QIC