Title |
A dynamic, embodied paradigm to investigate the role of serotonin in decision-making
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Published in |
Frontiers in Integrative Neuroscience, January 2013
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DOI | 10.3389/fnint.2013.00078 |
Pubmed ID | |
Authors |
Derrik E. Asher, Alexis B. Craig, Andrew Zaldivar, Alyssa A. Brewer, Jeffrey L. Krichmar |
Abstract |
Serotonin (5-HT) is a neuromodulator that has been attributed to cost assessment and harm aversion. In this review, we look at the role 5-HT plays in making decisions when subjects are faced with potential harmful or costly outcomes. We review approaches for examining the serotonergic system in decision-making. We introduce our group's paradigm used to investigate how 5-HT affects decision-making. In particular, our paradigm combines techniques from computational neuroscience, socioeconomic game theory, human-robot interaction, and Bayesian statistics. We will highlight key findings from our previous studies utilizing this paradigm, which helped expand our understanding of 5-HT's effect on decision-making in relation to cost assessment. Lastly, we propose a cyclic multidisciplinary approach that may aid in addressing the complexity of exploring 5-HT and decision-making by iteratively updating our assumptions and models of the serotonergic system through exhaustive experimentation. |
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Geographical breakdown
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
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Germany | 2 | 3% |
Spain | 1 | 1% |
United States | 1 | 1% |
Canada | 1 | 1% |
Unknown | 70 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 18 | 24% |
Researcher | 10 | 13% |
Student > Master | 9 | 12% |
Student > Bachelor | 7 | 9% |
Student > Doctoral Student | 5 | 7% |
Other | 12 | 16% |
Unknown | 14 | 19% |
Readers by discipline | Count | As % |
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Psychology | 20 | 27% |
Neuroscience | 13 | 17% |
Agricultural and Biological Sciences | 6 | 8% |
Engineering | 4 | 5% |
Computer Science | 4 | 5% |
Other | 9 | 12% |
Unknown | 19 | 25% |