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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cannabidiol, a Non-Psychoactive Cannabinoid Compound, Inhibits Proliferation and Invasion in U87-MG and T98G Glioma Cells through a Multitarget Effect
|
|---|---|
| Published in |
PLOS ONE, October 2013
|
| DOI | 10.1371/journal.pone.0076918 |
| Pubmed ID | |
| Authors |
Marta Solinas, Paola Massi, Valentina Cinquina, Marta Valenti, Daniele Bolognini, Marzia Gariboldi, Elena Monti, Tiziana Rubino, Daniela Parolaro |
| Abstract |
In the present study, we found that CBD inhibited U87-MG and T98G cell proliferation and invasiveness in vitro and caused a decrease in the expression of a set of proteins specifically involved in growth, invasion and angiogenesis. In addition, CBD treatment caused a dose-related down-regulation of ERK and Akt prosurvival signaling pathways in U87-MG and T98G cells and decreased hypoxia inducible factor HIF-1α expression in U87-MG cells. Taken together, these results provide new insights into the antitumor action of CBD, showing that this cannabinoid affects multiple tumoral features and molecular pathways. As CBD is a non-psychoactive phytocannabinoid that appears to be devoid of side effects, our results support its exploitation as an effective anti-cancer drug in the management of gliomas. |
X Demographics
The data shown below were collected from the profiles of 96 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 23 | 24% |
| Japan | 6 | 6% |
| Canada | 3 | 3% |
| Mexico | 3 | 3% |
| Russia | 3 | 3% |
| Montenegro | 1 | 1% |
| Ireland | 1 | 1% |
| Georgia | 1 | 1% |
| Chile | 1 | 1% |
| Other | 9 | 9% |
| Unknown | 45 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 90 | 94% |
| Science communicators (journalists, bloggers, editors) | 3 | 3% |
| Practitioners (doctors, other healthcare professionals) | 2 | 2% |
| Scientists | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| United Kingdom | 1 | <1% |
| Singapore | 1 | <1% |
| Unknown | 199 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 27 | 13% |
| Researcher | 26 | 13% |
| Student > Ph. D. Student | 24 | 12% |
| Student > Bachelor | 20 | 10% |
| Other | 13 | 6% |
| Other | 32 | 16% |
| Unknown | 63 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 29 | 14% |
| Medicine and Dentistry | 27 | 13% |
| Agricultural and Biological Sciences | 27 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 7% |
| Chemistry | 10 | 5% |
| Other | 26 | 13% |
| Unknown | 71 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 122. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2023.
All research outputs
#348,777
of 25,804,096 outputs
Outputs from PLOS ONE
#4,944
of 224,989 outputs
Outputs of similar age
#2,608
of 225,389 outputs
Outputs of similar age from PLOS ONE
#120
of 5,169 outputs
Altmetric has tracked 25,804,096 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 224,989 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 225,389 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 5,169 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.