Title |
A simple approach for coupling liquid chromatography and electron ionization mass spectrometry
|
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Published in |
Journal of the American Society for Mass Spectrometry, March 2002
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DOI | 10.1016/s1044-0305(01)00363-4 |
Pubmed ID | |
Authors |
Achille Cappiello, Giorgio Famiglini, Filippo Mangani, Pierangela Palma |
Abstract |
A miniaturized, aerosol based interface for directly coupling a liquid chromatograph with a mass spectrometer is presented. The interface is entirely within the electron ionization (EI) source of the mass spectrometer and no additional, external devices are needed. This simple and effective approach exploits micro-flow nebulization technology providing a new interface suitable for a variety of applications of environmental and biological interest. The new interface provides necessary linearity, ruggedness, sensitivity, and reproducibility of response for trace level analysis, and readily interpretable mass spectra for unambiguous identification of unknown compounds of small to medium molecular weight. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 2% |
Nigeria | 1 | 2% |
Unknown | 40 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 24% |
Student > Master | 8 | 19% |
Researcher | 4 | 10% |
Student > Doctoral Student | 2 | 5% |
Other | 2 | 5% |
Other | 4 | 10% |
Unknown | 12 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 16 | 38% |
Engineering | 4 | 10% |
Biochemistry, Genetics and Molecular Biology | 4 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Medicine and Dentistry | 1 | 2% |
Other | 1 | 2% |
Unknown | 14 | 33% |