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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Future of Thiazolidinedione Therapy in the Management of Type 2 Diabetes Mellitus
|
|---|---|
| Published in |
Current Diabetes Reports, April 2013
|
| DOI | 10.1007/s11892-013-0378-8 |
| Pubmed ID | |
| Authors |
Hanford Yau, Kathya Rivera, Romina Lomonaco, Kenneth Cusi |
| Abstract |
Since their approval, thiazolidinediones (TZDs) have been used extensively as insulin-sensitizers for the management of type 2 diabetes mellitus (T2DM). Activation of peroxisomal proliferator-activated receptor gamma (PPARγ) nuclear receptors by TZDs leads to a vast spectrum of metabolic and antiinflammatory effects. In the past decade, clinicians and scientists across the fields of metabolism, diabetes, liver disease (NAFLD), atherosclerosis, inflammation, infertility, and even cancer have had high hopes about the potential for TZDs to treat many of these diseases. However, an increasing awareness about undesirable "off-target" effects of TZDs have made us rethink their role and be more cautious about the long-term benefits and risks related to their use. This review examines the most relevant work on the benefits and risks associated with TZD treatment, with a focus on the only PPARγ agonist currently available (pioglitazone), aiming to offer the reader a balanced overview about the current and future role of TZDs in the management of insulin-resistant states and T2DM. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 140 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 25 | 18% |
| Student > Bachelor | 14 | 10% |
| Researcher | 13 | 9% |
| Student > Ph. D. Student | 13 | 9% |
| Student > Doctoral Student | 7 | 5% |
| Other | 24 | 17% |
| Unknown | 46 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 26% |
| Agricultural and Biological Sciences | 15 | 11% |
| Biochemistry, Genetics and Molecular Biology | 14 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 9% |
| Nursing and Health Professions | 3 | 2% |
| Other | 12 | 8% |
| Unknown | 48 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2024.
All research outputs
#4,500,467
of 22,733,113 outputs
Outputs from Current Diabetes Reports
#230
of 1,005 outputs
Outputs of similar age
#38,334
of 193,507 outputs
Outputs of similar age from Current Diabetes Reports
#1
of 8 outputs
Altmetric has tracked 22,733,113 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,005 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,507 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them