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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Relative resistance of HIV-1 founder viruses to control by interferon-alpha
|
|---|---|
| Published in |
Retrovirology, December 2013
|
| DOI | 10.1186/1742-4690-10-146 |
| Pubmed ID | |
| Authors |
Angharad E Fenton-May, Oliver Dibben, Tanja Emmerich, Haitao Ding, Katja Pfafferott, Marlen M Aasa-Chapman, Pierre Pellegrino, Ian Williams, Myron S Cohen, Feng Gao, George M Shaw, Beatrice H Hahn, Christina Ochsenbauer, John C Kappes, Persephone Borrow |
| Abstract |
Following mucosal human immunodeficiency virus type 1 (HIV-1) transmission, type 1 interferons (IFNs) are rapidly induced at sites of initial virus replication in the mucosa and draining lymph nodes. However, the role played by IFN-stimulated antiviral activity in restricting HIV-1 replication during the initial stages of infection is not clear. We hypothesized that if type 1 IFNs exert selective pressure on HIV-1 replication in the earliest stages of infection, the founder viruses that succeed in establishing systemic infection would be more IFN-resistant than viruses replicating during chronic infection, when type 1 IFNs are produced at much lower levels. To address this hypothesis, the relative resistance of virus isolates derived from HIV-1-infected individuals during acute and chronic infection to control by type 1 IFNs was analysed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Netherlands | 1 | <1% |
| Unknown | 139 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 40 | 28% |
| Researcher | 22 | 15% |
| Student > Master | 18 | 13% |
| Student > Bachelor | 12 | 8% |
| Student > Doctoral Student | 7 | 5% |
| Other | 15 | 11% |
| Unknown | 28 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 30% |
| Immunology and Microbiology | 33 | 23% |
| Medicine and Dentistry | 17 | 12% |
| Biochemistry, Genetics and Molecular Biology | 11 | 8% |
| Social Sciences | 3 | 2% |
| Other | 5 | 4% |
| Unknown | 31 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2013.
All research outputs
#18,355,685
of 22,733,113 outputs
Outputs from Retrovirology
#956
of 1,105 outputs
Outputs of similar age
#231,760
of 306,782 outputs
Outputs of similar age from Retrovirology
#53
of 63 outputs
Altmetric has tracked 22,733,113 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,105 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,782 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.