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Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine

Overview of attention for article published in JACC: Basic to Translational Science, March 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#30 of 828)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
5 news outlets
twitter
125 X users
facebook
7 Facebook pages

Citations

dimensions_citation
88 Dimensions

Readers on

mendeley
73 Mendeley
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Title
Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine
Published in
JACC: Basic to Translational Science, March 2017
DOI 10.1016/j.jacbts.2017.01.006
Pubmed ID
Authors

Brian R Weil, Rebeccah F Young, Xiaomeng Shen, Gen Suzuki, Jun Qu, Saurabh Malhotra, John M Canty

Abstract

In a porcine model of brief ischemia leading to reversible stunning in the absence of tissue necrosis, we demonstrated delayed release of cTnI that exceeded the 99(th) percentile for normals 60-minutes after reperfusion and rose to readily detectable levels 24-hours later. While tissue analysis at 60-minutes showed no evidence of infarction, TUNEL staining demonstrated isolated myocytes undergoing apoptosis, which was absent after 24-hours. These results demonstrate that cTnI elevations occur after ischemia of a duration that is insufficient to produce myocyte necrosis and reflect myocyte injury associated with delayed apoptosis in the absence of pathological evidence of infarction.

X Demographics

X Demographics

The data shown below were collected from the profiles of 125 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 16%
Researcher 8 11%
Student > Doctoral Student 7 10%
Student > Ph. D. Student 6 8%
Other 5 7%
Other 14 19%
Unknown 21 29%
Readers by discipline Count As %
Medicine and Dentistry 28 38%
Agricultural and Biological Sciences 5 7%
Nursing and Health Professions 4 5%
Biochemistry, Genetics and Molecular Biology 3 4%
Engineering 3 4%
Other 7 10%
Unknown 23 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 107. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2018.
All research outputs
#401,869
of 25,795,662 outputs
Outputs from JACC: Basic to Translational Science
#30
of 828 outputs
Outputs of similar age
#8,348
of 324,309 outputs
Outputs of similar age from JACC: Basic to Translational Science
#1
of 21 outputs
Altmetric has tracked 25,795,662 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 828 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,309 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.