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Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma

Overview of attention for article published in PLOS ONE, December 2013
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1 X user

Citations

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47 Mendeley
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Title
Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma
Published in
PLOS ONE, December 2013
DOI 10.1371/journal.pone.0082406
Pubmed ID
Authors

Katelin N. Townsend, Jaeline E. Spowart, Hassan Huwait, Sima Eshragh, Nathan R. West, Mary A. Elrick, Steve E. Kalloger, Michael Anglesio, Peter H. Watson, David G. Huntsman, Julian J. Lum

Abstract

When T cells infiltrate the tumor environment they encounter a myriad of metabolic stressors including hypoxia. Overcoming the limitations imposed by an inadequate tumor vasculature that contributes to these stressors may be a crucial step to immune cells mounting an effective anti-tumor response. We sought to determine whether the functional capacity of tumor infiltrating lymphocytes (TIL) could be influenced by the tumor vasculature and correlated this with survival in patients with ovarian cancer.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Pakistan 1 2%
Unknown 46 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 30%
Researcher 8 17%
Student > Bachelor 6 13%
Student > Master 4 9%
Professor > Associate Professor 3 6%
Other 7 15%
Unknown 5 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 38%
Immunology and Microbiology 7 15%
Biochemistry, Genetics and Molecular Biology 5 11%
Medicine and Dentistry 5 11%
Psychology 2 4%
Other 3 6%
Unknown 7 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2013.
All research outputs
#20,215,721
of 22,738,543 outputs
Outputs from PLOS ONE
#173,188
of 194,081 outputs
Outputs of similar age
#266,408
of 306,693 outputs
Outputs of similar age from PLOS ONE
#4,861
of 5,627 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 194,081 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,693 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,627 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.