↓ Skip to main content

Evaluation of the association between the TAS1R2 and TAS1R3 variants and food intake and nutritional status in children

Overview of attention for article published in Genetics and molecular biology, January 2017
Altmetric Badge

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
15 Dimensions

Readers on

mendeley
48 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Evaluation of the association between the TAS1R2 and TAS1R3 variants and food intake and nutritional status in children
Published in
Genetics and molecular biology, January 2017
DOI 10.1590/1678-4685-gmb-2016-0205
Pubmed ID
Authors

Melo, Silvia V., Agnes, Grasiela, Vitolo, Márcia R., Mattevi, Vanessa S., Campagnolo, Paula D.B., Almeida, Silvana

Abstract

Taste perception plays a key role in determining individual food preferences and dietary habits and may influence nutritional status. This study aimed to investigate the association of TAS1R2 (Ile191Val - rs35874116) and TAS1R3 (-1266 C/T - rs35744813) variants with food intake and nutritional status in children followed from birth until 7.7 years old. The nutritional status and food intake data of 312 children were collected at three developmental stages (1, 3.9 and 7.7 years old). DNA was extracted from blood samples and the polymorphisms were analyzed by real-time polymerase chain reactions (qPCR) using hydrolysis probes as the detection method. Food intake and nutritional status were compared among individuals with different single nucleotide polymorphism (SNP) genotypes. At 3.9 years old, children homozygous (Val/Val) for the TAS1R2 Ile191Val polymorphism ingested less sugar and sugar-dense foods than children who were *Ile carriers. This finding demonstrated that a genetic variant of the T1R2 taste receptor is associated with the intake of different amounts of high sugar-content foods in childhood. This association may provide new perspectives for studying dietary patterns and nutritional status in childhood.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 11 23%
Student > Master 10 21%
Student > Ph. D. Student 4 8%
Student > Doctoral Student 3 6%
Professor 3 6%
Other 8 17%
Unknown 9 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 21%
Agricultural and Biological Sciences 7 15%
Medicine and Dentistry 7 15%
Nursing and Health Professions 3 6%
Neuroscience 3 6%
Other 3 6%
Unknown 15 31%