Title |
Comparative analysis of apoptotic changes in peripheral immune organs and lungs following experimental infection of piglets with highly pathogenic and classical porcine reproductive and respiratory syndrome virus
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Published in |
Virology Journal, January 2014
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DOI | 10.1186/1743-422x-11-2 |
Pubmed ID | |
Authors |
Gang Wang, Yuli He, Yabin Tu, Yonggang Liu, En-Min Zhou, Zifeng Han, Chenggang Jiang, Shujie Wang, Wenda Shi, Xuehui Cai |
Abstract |
Our previous studies have demonstrated that piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) may develop significant thymus atrophy, which related to thymocytes apoptosis. However, apart from that detected in the thymus, there are no reports describing cell apoptosis induced by HP-PRRSV infection. In this study, we analyzed comparatively the pathological changes, cell apoptosis and viral load in peripheral immune organs including tonsil, inguinal lymph nodes (ILNs) and spleen and lungs following experimental infection of piglets with HP-PRRSV HuN4 and classical PRRSV CH-1a. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 4% |
Unknown | 24 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor | 3 | 12% |
Professor > Associate Professor | 3 | 12% |
Researcher | 3 | 12% |
Student > Ph. D. Student | 3 | 12% |
Student > Master | 2 | 8% |
Other | 4 | 16% |
Unknown | 7 | 28% |
Readers by discipline | Count | As % |
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Veterinary Science and Veterinary Medicine | 6 | 24% |
Agricultural and Biological Sciences | 4 | 16% |
Engineering | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Other | 2 | 8% |
Unknown | 7 | 28% |