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AMERICAN CUTANEOUS LEISHMANIASIS WITH UNUSUAL CLINICAL PRESENTATION AND RESPONSE TO TREATMENT

Overview of attention for article published in Revista do Instituto de Medicina Tropical de São Paulo, January 2016
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Title
AMERICAN CUTANEOUS LEISHMANIASIS WITH UNUSUAL CLINICAL PRESENTATION AND RESPONSE TO TREATMENT
Published in
Revista do Instituto de Medicina Tropical de São Paulo, January 2016
DOI 10.1590/s1678-9946201658020
Pubmed ID
Authors

Andrea Claudia Bekner Silva FERNANDES, Raíssa Bocchi PEDROSO, Eneide Aparecida Sabaini VENAZZI, Paulo Donizeti ZANZARINI, Sandra Mara Alessi ARISTIDES, Maria Valdrinez Campana LONARDONI, Thaís Gomes Verzignassi SILVEIRA

Abstract

The clinical manifestations and prognosis of cutaneous leishmaniasis (CL) can be influenced by the immune response of the patient and the species of the parasite. A case of atypical clinical presentation of CL, with development of non-characteristic lesions, poor response to therapy, and a long time to resolution is reported. Confirmatory laboratory tests included parasite detection, indirect immunofluorescence, Montenegro skin test, polymerase chain reaction, and parasite identification by multilocus enzyme electrophoresis. The parasite was identified as Leishmaniabraziliensis. The lesion was unresponsive to three complete courses of N-methylglucamine antimoniate intramuscular, and to treatment with pentamidine. The patient did not tolerate amphotericin B. The lesion finally receded after treatment with intravenous N-methylglucamine antimoniate. It is essential to ensure the accuracy of diagnosis and the appropriate treatment, which can include the use a second choice drug or a different route of administration.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 21%
Student > Doctoral Student 4 17%
Researcher 3 13%
Professor > Associate Professor 2 8%
Other 2 8%
Other 4 17%
Unknown 4 17%
Readers by discipline Count As %
Medicine and Dentistry 6 25%
Immunology and Microbiology 5 21%
Biochemistry, Genetics and Molecular Biology 4 17%
Agricultural and Biological Sciences 3 13%
Veterinary Science and Veterinary Medicine 1 4%
Other 0 0%
Unknown 5 21%