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Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis

Overview of attention for article published in Critical Care, January 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
2 tweeters
patent
5 patents

Citations

dimensions_citation
84 Dimensions

Readers on

mendeley
152 Mendeley
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Title
Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis
Published in
Critical Care, January 2011
DOI 10.1186/cc10274
Pubmed ID
Authors

Allison Sutherland, Mervyn Thomas, Roslyn A Brandon, Richard B Brandon, Jeffrey Lipman, Benjamin Tang, Anthony McLean, Ranald Pascoe, Gareth Price, Thu Nguyen, Glenn Stone, Deon Venter

Abstract

Sepsis is a complex immunological response to infection characterized by early hyper-inflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on Systemic Inflammatory Response Syndrome (SIRS) differentiation. Pre-clinical research using an equine sepsis model identified a panel of gene expression biomarkers that define the early aberrant immune activation. Thus, the primary objective was to apply these gene expression biomarkers to distinguish patients with sepsis from those who had undergone major open surgery and had clinical outcomes consistent with systemic inflammation due to physical trauma and wound healing.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
France 2 1%
Brazil 2 1%
Australia 1 <1%
Norway 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
Germany 1 <1%
Unknown 141 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 32 21%
Student > Ph. D. Student 29 19%
Student > Master 20 13%
Other 11 7%
Professor 10 7%
Other 34 22%
Unknown 16 11%
Readers by discipline Count As %
Medicine and Dentistry 62 41%
Agricultural and Biological Sciences 29 19%
Biochemistry, Genetics and Molecular Biology 9 6%
Computer Science 6 4%
Engineering 4 3%
Other 21 14%
Unknown 21 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2019.
All research outputs
#1,631,714
of 14,807,872 outputs
Outputs from Critical Care
#1,498
of 4,663 outputs
Outputs of similar age
#29,454
of 259,933 outputs
Outputs of similar age from Critical Care
#33
of 146 outputs
Altmetric has tracked 14,807,872 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,663 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,933 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 146 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.