Title |
Endometrial adenocarcinoma with choriocarcinomatous differentiation in the uterus of a goat
|
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Published in |
Journal of Veterinary Medical Science, May 2017
|
DOI | 10.1292/jvms.17-0015 |
Pubmed ID | |
Authors |
Masashi KAWASHIMA, Risa SEGAWA, Toshinori YOSHIDA, Hirotada MURAYAMA, Rei NAGAHARA, Masayuki KIMURA, ENDO Natsumi, Tomomi TANAKA, Makoto SHIBUTANI |
Abstract |
An 11-year-old female goat had invasive and metastatic endometrial adenocarcinoma in the uterus. There was a notable proliferation of endometrial epithelial cells in a tubular growth pattern, with a desmoplastic response. The endometrial epithelial tumor cells metastasized to the kidney, liver and lung. In contrast to the primary and metastatic tumor cells, pleomorphic tumor cells with a choriocarcinoma-like growth pattern infiltrated the mesometrium. Cell proliferation activity was high in both types of tumor cells. Both types of tumor cells expressed cytokeratins AE1/AE3, 7 and CAM5.2; choriocarcinomatous cells also had positive immunoreactions to human chorionic gonadotropin, human placental alkaline phosphatase and α-inhibin. The present case was diagnosed as endometrial adenocarcinoma with choriocarcinomatous differentiation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 2 | 14% |
Professor | 1 | 7% |
Lecturer | 1 | 7% |
Other | 1 | 7% |
Researcher | 1 | 7% |
Other | 1 | 7% |
Unknown | 7 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 4 | 29% |
Agricultural and Biological Sciences | 3 | 21% |
Engineering | 1 | 7% |
Unknown | 6 | 43% |