Chapter 1 RLS/WED: Criteria, Differential Diagnosis and Prevalence of Occurrence

Chapter 2 Mental Health Disorders Associated with RLS

Chapter 3 Sleep Impact: Insomnia, Hypersomnia, Sleep Attacks, and Circadian Disorders

Chapter 4 Cognitive Functioning

Chapter 5 Health-Related Quality of Life and Depression Symptom Measures for the Assessment of Treatment in Restless Legs Syndrome/Willis–Ekbom Disease

Chapter 6 Epidemiologic Evidence in Cardiovascular Disease

Chapter 8 Willis–Ekbom Disease, Periodic Limb Movements of Sleep, and Cardiovascular Disease: Putative Mechanisms and Implications for Long-Term Treatment

Chapter 9 Peripheral Muscle Changes

Chapter 10 Outcome and Mortality in Renal Failure Related RLS

Chapter 11 Long-Term Efficacy of Pharmacological Treatment

Chapter 12 Augmentation: Criteria, Prevalence, and Differential Diagnosis

Chapter 13 Treatment Options When Short-Acting Dopamine Agonists Fail or Cause Augmentation: Switching or Adding Medications

Chapter 14 Management of Augmentation

Chapter 15 Managing Concurrent Medications

Chapter 16 Impulsive Behaviors: Definition, Prevalence, Neurobiology, and Management

Chapter 17 Impulse Control Behavior in Movement Disorders: Focus on Restless Leg Syndrome

Chapter 18 Management of RLS During Pregnancy

Chapter 19 Management of RLS in Children (Unique Features)