You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chronic Spinal Cord Electrical Stimulation Protects Against 6-hydroxydopamine Lesions
|
|---|---|
| Published in |
Scientific Reports, January 2014
|
| DOI | 10.1038/srep03839 |
| Pubmed ID | |
| Authors |
Amol P. Yadav, Romulo Fuentes, Hao Zhang, Thais Vinholo, Chi-Han Wang, Marco Aurelio M. Freire, Miguel A. L. Nicolelis |
| Abstract |
Although L-dopa continues to be the gold standard for treating motor symptoms of Parkinson's disease (PD), it presents long-term complications. Deep brain stimulation is effective, but only a small percentage of idiopathic PD patients are eligible. Based on results in animal models and a handful of patients, dorsal column stimulation (DCS) has been proposed as a potential therapy for PD. To date, the long-term effects of DCS in animal models have not been quantified. Here, we report that DCS applied twice a week in rats treated with bilateral 6-OHDA striatal infusions led to a significant improvement in symptoms. DCS-treated rats exhibited a higher density of dopaminergic innervation in the striatum and higher neuronal cell count in the substantia nigra pars compacta compared to a control group. These results suggest that DCS has a chronic therapeutical and neuroprotective effect, increasing its potential as a new clinical option for treating PD patients. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 33% |
| Brazil | 2 | 33% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 5% |
| Canada | 1 | 1% |
| Unknown | 79 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 21% |
| Student > Ph. D. Student | 13 | 15% |
| Student > Master | 10 | 12% |
| Student > Bachelor | 9 | 11% |
| Student > Doctoral Student | 7 | 8% |
| Other | 15 | 18% |
| Unknown | 12 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 19 | 23% |
| Medicine and Dentistry | 17 | 20% |
| Agricultural and Biological Sciences | 11 | 13% |
| Engineering | 11 | 13% |
| Psychology | 3 | 4% |
| Other | 7 | 8% |
| Unknown | 16 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 78. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2018.
All research outputs
#458,788
of 22,741,406 outputs
Outputs from Scientific Reports
#5,188
of 122,606 outputs
Outputs of similar age
#5,107
of 305,708 outputs
Outputs of similar age from Scientific Reports
#31
of 720 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 122,606 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,708 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 720 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.