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A Review of Adjunctive CNS Medications Used for the Treatment of Post-Surgical Pain

Overview of attention for article published in CNS Drugs, June 2017
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Title
A Review of Adjunctive CNS Medications Used for the Treatment of Post-Surgical Pain
Published in
CNS Drugs, June 2017
DOI 10.1007/s40263-017-0440-1
Pubmed ID
Authors

Ajit Rai, Howard Meng, Aliza Weinrib, Marina Englesakis, Dinesh Kumbhare, Liza Grosman-Rimon, Joel Katz, Hance Clarke

Abstract

Inadequate post-operative pain management can have significant impacts on patients' quality of life. Effective management of acute pain after surgery is important for early mobilization and discharge from hospital, patient satisfaction, and overall well-being. Utilizing multimodal analgesic strategies has become the mainstay of acute post-operative pain management. A comprehensive search was performed, assessing the published or otherwise publically available literature on different central nervous system (CNS) drugs [excluding opioids, non-steroidal anti-inflammatory drugs (NSAIDs), and acetaminophen] and their uses to treat acute post-surgical pain. Included among the drugs evaluated in this review are anticonvulsants, N-methyl-D-aspartic acid (NMDA) agonists, local anesthetics, α2-agonists, cannabinoids, serotonin-noradrenaline reuptake inhibitors (SNRIs), and serotonin-noradrenaline-dopamine reuptake inhibitors (SNDRIs). Timing, dosing, routes of administration, as well as mechanisms of action are discussed for these CNS drugs.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 69 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 13%
Other 7 10%
Student > Postgraduate 7 10%
Researcher 5 7%
Student > Doctoral Student 5 7%
Other 17 25%
Unknown 19 28%
Readers by discipline Count As %
Medicine and Dentistry 30 43%
Nursing and Health Professions 6 9%
Biochemistry, Genetics and Molecular Biology 2 3%
Computer Science 2 3%
Unspecified 1 1%
Other 7 10%
Unknown 21 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2018.
All research outputs
#15,462,982
of 22,977,819 outputs
Outputs from CNS Drugs
#1,096
of 1,314 outputs
Outputs of similar age
#199,459
of 317,446 outputs
Outputs of similar age from CNS Drugs
#13
of 22 outputs
Altmetric has tracked 22,977,819 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,314 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,446 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.