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Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus…

Overview of attention for article published in Parasites & Vectors, January 2014
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2 X users

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23 Mendeley
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Title
Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae
Published in
Parasites & Vectors, January 2014
DOI 10.1186/1756-3305-7-43
Pubmed ID
Authors

Sridhar Arumugam, Bin Zhan, David Abraham, Danielle Ward, Sara Lustigman, Thomas R Klei

Abstract

Cysteine protease inhibitors of Brugia malayi have been ascribed to be involved in parasite development as well as to immunomodulate the host's immune response. In Onchocerca volvulus, Onchocystatin has been shown to induce partial protection in the mouse diffusion chamber vaccination model. In the present study we investigated the impact of vaccination with recombinant Bm-CPI-1 and Bm-CPI-2 proteins on protection against a subcutaneous challenge of B. malayi third stage larvae in gerbils.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 22%
Researcher 4 17%
Student > Doctoral Student 2 9%
Student > Master 2 9%
Student > Bachelor 1 4%
Other 4 17%
Unknown 5 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 30%
Medicine and Dentistry 2 9%
Unspecified 1 4%
Environmental Science 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 5 22%
Unknown 6 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2014.
All research outputs
#17,710,421
of 22,741,406 outputs
Outputs from Parasites & Vectors
#3,799
of 5,447 outputs
Outputs of similar age
#219,872
of 305,702 outputs
Outputs of similar age from Parasites & Vectors
#143
of 219 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,447 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,702 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 219 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.