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dictyExpress: a web-based platform for sequence data management and analytics in Dictyostelium and beyond

Overview of attention for article published in BMC Bioinformatics, June 2017
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Title
dictyExpress: a web-based platform for sequence data management and analytics in Dictyostelium and beyond
Published in
BMC Bioinformatics, June 2017
DOI 10.1186/s12859-017-1706-9
Pubmed ID
Authors

Miha Stajdohar, Rafael D. Rosengarten, Janez Kokosar, Luka Jeran, Domen Blenkus, Gad Shaulsky, Blaz Zupan

Abstract

Dictyostelium discoideum, a soil-dwelling social amoeba, is a model for the study of numerous biological processes. Research in the field has benefited mightily from the adoption of next-generation sequencing for genomics and transcriptomics. Dictyostelium biologists now face the widespread challenges of analyzing and exploring high dimensional data sets to generate hypotheses and discovering novel insights. We present dictyExpress (2.0), a web application designed for exploratory analysis of gene expression data, as well as data from related experiments such as Chromatin Immunoprecipitation sequencing (ChIP-Seq). The application features visualization modules that include time course expression profiles, clustering, gene ontology enrichment analysis, differential expression analysis and comparison of experiments. All visualizations are interactive and interconnected, such that the selection of genes in one module propagates instantly to visualizations in other modules. dictyExpress currently stores the data from over 800 Dictyostelium experiments and is embedded within a general-purpose software framework for management of next-generation sequencing data. dictyExpress allows users to explore their data in a broader context by reciprocal linking with dictyBase-a repository of Dictyostelium genomic data. In addition, we introduce a companion application called GenBoard, an intuitive graphic user interface for data management and bioinformatics analysis. dictyExpress and GenBoard enable broad adoption of next generation sequencing based inquiries by the Dictyostelium research community. Labs without the means to undertake deep sequencing projects can mine the data available to the public. The entire information flow, from raw sequence data to hypothesis testing, can be accomplished in an efficient workspace. The software framework is generalizable and represents a useful approach for any research community. To encourage more wide usage, the backend is open-source, available for extension and further development by bioinformaticians and data scientists.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 30%
Student > Bachelor 8 18%
Researcher 6 14%
Student > Doctoral Student 3 7%
Other 2 5%
Other 8 18%
Unknown 4 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 27%
Agricultural and Biological Sciences 11 25%
Computer Science 6 14%
Engineering 3 7%
Unspecified 2 5%
Other 5 11%
Unknown 5 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2017.
All research outputs
#20,190,425
of 24,818,814 outputs
Outputs from BMC Bioinformatics
#6,600
of 7,593 outputs
Outputs of similar age
#249,108
of 322,767 outputs
Outputs of similar age from BMC Bioinformatics
#94
of 112 outputs
Altmetric has tracked 24,818,814 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,593 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
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