General and specific effects of early-life psychosocial adversities on adolescent grey matter volume

Overview of attention for article published in NeuroImage: Clinical, January 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#4 of 505)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
7 news outlets
blogs
4 blogs
twitter
24 tweeters
facebook
1 Facebook page

Readers on

mendeley
85 Mendeley
Title
General and specific effects of early-life psychosocial adversities on adolescent grey matter volume
Published in
NeuroImage: Clinical, January 2014
DOI 10.1016/j.nicl.2014.01.001
Pubmed ID
Authors

Walsh ND, Dalgleish T, Lombardo MV, Dunn VJ, Van Harmelen AL, Ban M, Goodyer IM

Abstract

Exposure to childhood adversities (CA) is associated with subsequent alterations in regional brain grey matter volume (GMV). Prior studies have focused mainly on severe neglect and maltreatment. The aim of this study was to determine in currently healthy adolescents if exposure to more common forms of CA results in reduced GMV. Effects on brain structure were investigated using voxel-based morphometry in a cross-sectional study of youth recruited from a population-based longitudinal cohort. 58 participants (mean age = 18.4) with (n = 27) or without (n = 31) CA exposure measured retrospectively from maternal interview were included in the study. Measures of recent negative life events (RNLE) recorded at 14 and 17 years, current depressive symptoms, gender, participant/parental psychiatric history, current family functioning perception and 5-HTTLPR genotype were covariates in analyses. A multivariate analysis of adversities demonstrated a general association with a widespread distributed neural network consisting of cortical midline, lateral frontal, temporal, limbic, and cerebellar regions. Univariate analyses showed more specific associations between adversity measures and regional GMV: CA specifically demonstrated reduced vermis GMV and past psychiatric history with reduced medial temporal lobe volume. In contrast RNLE aged 14 was associated with increased lateral cerebellar and anterior cingulate GMV. We conclude that exposure to moderate levels of childhood adversities occurring during childhood and early adolescence exerts effects on the developing adolescent brain. Reducing exposure to adverse social environments during early life may optimize typical brain development and reduce subsequent mental health risks in adult life.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
United Kingdom 2 2%
Germany 1 1%
Australia 1 1%
Mexico 1 1%
Japan 1 1%
New Zealand 1 1%
Unknown 75 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 21%
Researcher 18 21%
Student > Master 11 13%
Student > Doctoral Student 10 12%
Student > Postgraduate 9 11%
Other 19 22%
Readers by discipline Count As %
Psychology 45 53%
Medicine and Dentistry 13 15%
Agricultural and Biological Sciences 9 11%
Social Sciences 6 7%
Neuroscience 5 6%
Other 7 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 107. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2014.
All research outputs
#41,908
of 5,367,091 outputs
Outputs from NeuroImage: Clinical
#4
of 505 outputs
Outputs of similar age
#1,736
of 144,971 outputs
Outputs of similar age from NeuroImage: Clinical
#1
of 29 outputs
Altmetric has tracked 5,367,091 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 505 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 144,971 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.