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The Actin Cytoskeleton

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Attention for Chapter 26: ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins
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Chapter title
ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins
Chapter number 26
Book title
The Actin Cytoskeleton
Published in
Handbook of experimental pharmacology, January 2016
DOI 10.1007/164_2016_26
Pubmed ID
Book ISBNs
978-3-31-946369-8, 978-3-31-946371-1
Authors

Klaus Aktories, Carsten Schwan, Alexander E. Lang

Editors

Brigitte M. Jockusch

Abstract

Actin and the actin cytoskeleton play fundamental roles in host-pathogen interactions. Proper function of the actin cytoskeleton is crucial for innate and acquired immune defense. Bacterial toxins attack the actin cytoskeleton by targeting regulators of actin. Moreover, actin is directly modified by various bacterial protein toxins and effectors, which cause ADP-ribosylation or cross-linking of actin. Modification of actin can result in inhibition or stimulation of actin polymerization. Toxins, acting directly on actin, are reviewed.

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Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 50%
Professor 1 17%
Unknown 2 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 50%
Veterinary Science and Veterinary Medicine 1 17%
Unknown 2 33%