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Mendeley readers
Attention Score in Context
Title |
Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90
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Published in |
PLOS ONE, July 2010
|
DOI | 10.1371/journal.pone.0011772 |
Pubmed ID | |
Authors |
Daniela Trisciuoglio, Chiara Gabellini, Marianna Desideri, Elio Ziparo, Gabriella Zupi, Donatella Del Bufalo |
Abstract |
Hypoxia-Inducible Factor 1 (HIF-1) is a transcription factor that is a critical mediator of the cellular response to hypoxia. Enhanced levels of HIF-1alpha, the oxygen-regulated subunit of HIF-1, is often associated with increased tumour angiogenesis, metastasis, therapeutic resistance and poor prognosis. It is in this context that we previously demonstrated that under hypoxia, bcl-2 protein promotes HIF-1/Vascular Endothelial Growth Factor (VEGF)-mediated tumour angiogenesis. |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 2 | 3% |
Japan | 1 | 1% |
United States | 1 | 1% |
Poland | 1 | 1% |
Unknown | 67 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 24 | 33% |
Researcher | 13 | 18% |
Student > Bachelor | 6 | 8% |
Professor | 4 | 6% |
Student > Master | 4 | 6% |
Other | 7 | 10% |
Unknown | 14 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 32% |
Medicine and Dentistry | 15 | 21% |
Biochemistry, Genetics and Molecular Biology | 13 | 18% |
Engineering | 2 | 3% |
Chemistry | 2 | 3% |
Other | 4 | 6% |
Unknown | 13 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2022.
All research outputs
#3,514,459
of 22,743,667 outputs
Outputs from PLOS ONE
#42,930
of 194,093 outputs
Outputs of similar age
#12,597
of 93,941 outputs
Outputs of similar age from PLOS ONE
#207
of 746 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 194,093 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 93,941 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 746 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.