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Aspirin Use in Heart Failure

Overview of attention for article published in Circulation: Heart Failure, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
1 news outlet
policy
1 policy source
twitter
22 tweeters
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
71 Mendeley
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Title
Aspirin Use in Heart Failure
Published in
Circulation: Heart Failure, March 2014
DOI 10.1161/circheartfailure.113.000132
Pubmed ID
Authors

Margaret Bermingham, Mary Katherine Shanahan, Eoin O’Connell, Ian Dawkins, Saki Miwa, Rory O’Hanlon, John Gilmer, Kenneth McDonald, Mark Ledwidge

Abstract

Background- Aspirin use in heart failure (HF) is controversial. The drug has proven benefit in comorbidities associated with HF; however, retrospective analysis of angiotensin-converting enzyme inhibitor trials and prospective comparisons with warfarin have shown increased risk of morbidity with aspirin use. This study aims to evaluate the association of low-dose aspirin with mortality and morbidity risk in a large community-based cohort. Methods and Results- This was a retrospective cohort study of patients attending an HF disease management program. Aspirin use at baseline and its association with mortality and HF hospitalization in the population was examined. Of 1476 patients (mean age, 70.4±12.4 years; 63% men), 892 (60.4%) were prescribed aspirin. Low-dose aspirin (75 mg/d) was prescribed to 828 (92.8%) patients. Median follow-up time was 2.6 (0.8-4.5) years. During the follow-up period, 464 (31.4%) patients died. In adjusted analysis, low-dose aspirin use was associated with reduced mortality risk compared with nonaspirin use (hazard ratio=0.58; 95% confidence interval, 0.46-0.74), and this was confirmed by a propensity-matched subgroup analysis. Low-dose aspirin use was associated with reduced risk of HF hospitalization compared with nonaspirin use in the total population (adjusted hazard ratio=0.70; 95% confidence interval, 0.54-0.90). In adjusted analysis, there was no difference in mortality or HF hospitalization between high-dose aspirin users (>75 mg/d) and nonaspirin users. Conclusions- In this study, low-dose aspirin therapy was associated with a significant reduction in mortality and morbidity risk during long-term follow-up. These results suggest that low-dose aspirin may have a continuing role in secondary prevention in HF and underline the need for more trials of low-dose aspirin use in HF.

Twitter Demographics

The data shown below were collected from the profiles of 22 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Germany 1 1%
Unknown 69 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 21%
Student > Bachelor 13 18%
Student > Master 11 15%
Other 7 10%
Student > Ph. D. Student 4 6%
Other 11 15%
Unknown 10 14%
Readers by discipline Count As %
Medicine and Dentistry 30 42%
Pharmacology, Toxicology and Pharmaceutical Science 12 17%
Nursing and Health Professions 7 10%
Agricultural and Biological Sciences 2 3%
Engineering 2 3%
Other 6 8%
Unknown 12 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2018.
All research outputs
#965,927
of 19,101,906 outputs
Outputs from Circulation: Heart Failure
#136
of 1,211 outputs
Outputs of similar age
#13,258
of 270,591 outputs
Outputs of similar age from Circulation: Heart Failure
#4
of 31 outputs
Altmetric has tracked 19,101,906 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,211 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.9. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,591 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.