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Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-κB pathway

Overview of attention for article published in BMC Cancer, February 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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Citations

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63 Mendeley
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Title
Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-κB pathway
Published in
BMC Cancer, February 2014
DOI 10.1186/1471-2407-14-96
Pubmed ID
Authors

Ting Li, Qunling Zhang, Jian Zhang, Gong Yang, Zhimin Shao, Jianmin Luo, Minhao Fan, Chen Ni, Zhenhua Wu, Xichun Hu

Abstract

There are a lot of unmet needs in patients with triple-negative breast cancer (TNBC). Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPAR-α) agonist, has been used for decades to treat hypertriglyceridaemia and mixed dyslipidaemia. Recent studies show that it might have anti-tumor effects, however, the mechanism remains unclear. Here, we assessed the ability of fenofibrate to induce apoptosis of TNBC in vitro and in vivo and explored involved mechanisms.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 62 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 21%
Student > Ph. D. Student 12 19%
Student > Doctoral Student 4 6%
Professor 4 6%
Student > Bachelor 3 5%
Other 11 17%
Unknown 16 25%
Readers by discipline Count As %
Medicine and Dentistry 11 17%
Biochemistry, Genetics and Molecular Biology 10 16%
Agricultural and Biological Sciences 9 14%
Pharmacology, Toxicology and Pharmaceutical Science 6 10%
Nursing and Health Professions 4 6%
Other 9 14%
Unknown 14 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2014.
All research outputs
#12,601,452
of 22,745,803 outputs
Outputs from BMC Cancer
#2,606
of 8,272 outputs
Outputs of similar age
#104,161
of 222,819 outputs
Outputs of similar age from BMC Cancer
#46
of 135 outputs
Altmetric has tracked 22,745,803 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,272 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 222,819 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 135 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.