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Imaging Dynamic Molecular Signaling by the Cdc42 GTPase within the Developing CNS

Overview of attention for article published in PLOS ONE, February 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
4 news outlets
blogs
1 blog
twitter
7 X users
facebook
1 Facebook page

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
23 Mendeley
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Title
Imaging Dynamic Molecular Signaling by the Cdc42 GTPase within the Developing CNS
Published in
PLOS ONE, February 2014
DOI 10.1371/journal.pone.0088870
Pubmed ID
Authors

Nima Sharifai, Hasitha Samarajeewa, Daichi Kamiyama, Tzyy-Chyn Deng, Maria Boulina, Akira Chiba

Abstract

Protein interactions underlie the complexity of neuronal function. Potential interactions between specific proteins in the brain are predicted from assays based on genetic interaction and/or biochemistry. Genetic interaction reveals endogenous, but not necessarily direct, interactions between the proteins. Biochemistry-based assays, on the other hand, demonstrate direct interactions between proteins, but often outside their native environment or without a subcellular context. We aimed to achieve the best of both approaches by visualizing protein interaction directly within the brain of a live animal. Here, we show a proof-of-principle experiment in which the Cdc42 GTPase associates with its alleged partner WASp within neurons during the time and space that coincide with the newly developing CNS.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hong Kong 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 26%
Student > Master 4 17%
Researcher 4 17%
Student > Postgraduate 2 9%
Librarian 2 9%
Other 4 17%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 35%
Biochemistry, Genetics and Molecular Biology 6 26%
Neuroscience 3 13%
Psychology 2 9%
Immunology and Microbiology 1 4%
Other 2 9%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2014.
All research outputs
#878,564
of 23,864,146 outputs
Outputs from PLOS ONE
#11,826
of 203,924 outputs
Outputs of similar age
#9,038
of 226,766 outputs
Outputs of similar age from PLOS ONE
#392
of 5,740 outputs
Altmetric has tracked 23,864,146 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 203,924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.5. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,766 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 5,740 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.