Title |
Food allergy in a child with de novo KAT6A mutation
|
---|---|
Published in |
Clinical and Translational Allergy, June 2017
|
DOI | 10.1186/s13601-017-0155-x |
Pubmed ID | |
Authors |
Varpu Elenius, Tuire Lähdesmäki, Marja Hietala, Tuomas Jartti |
Abstract |
Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is known to cause a syndrome characterized by developmental delay, hypotonia, cardiac defects, microcephaly, specific facial features and early feeding problems. However, these feeding problems have not earlier been specified. We present the first reported case of a DBPCFC confirmed food allergy in a child with KAT6A mutation whose feeding problems resolved with elimination diet. The present case does not establish proof of cause, but highlights the importance of careful clinical diagnostics despite other possible causes for feeding problems. Recognizing that early feeding problems these patients regularly have might be caused by food allergy is important for outcome and quality of life for these patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Austria | 1 | 33% |
Switzerland | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 3 | 23% |
Student > Ph. D. Student | 2 | 15% |
Researcher | 2 | 15% |
Lecturer | 1 | 8% |
Student > Postgraduate | 1 | 8% |
Other | 0 | 0% |
Unknown | 4 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 23% |
Medicine and Dentistry | 2 | 15% |
Nursing and Health Professions | 2 | 15% |
Mathematics | 1 | 8% |
Arts and Humanities | 1 | 8% |
Other | 0 | 0% |
Unknown | 4 | 31% |