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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Unusual Lipid A from a Cold‐Adapted Bacterium: Detailed Structural Characterization
|
|---|---|
| Published in |
ChemBioChem, July 2017
|
| DOI | 10.1002/cbic.201700287 |
| Pubmed ID | |
| Authors |
Angela Casillo, Marcello Ziaco, Buko Lindner, Ermenegilda Parrilli, Dominik Schwudke, Aurora Holgado, Lynn Verstrepen, Filomena Sannino, Rudi Beyaert, Rosa Lanzetta, Maria Luisa Tutino, Maria Michela Corsaro |
| Abstract |
Colwellia psychrerythraea 34H is a Gram-negative cold-adapted microorganism that adopts many strategies to cope with the limitations due to the low temperatures of its habitat. In this study, we reported the complete characterization of the lipid A moiety from the lipopolysaccharide of Colwellia, to find out if structural features could be linked to the cold-adaptation strategy. The lipid A and its partially deacylated derivative were completely characterized by means of high resolution mass spectrometry, NMR spectroscopy, and chemical analysis. An unusual structure, consisting of 3-hydroxy unsaturated tetradecenoic acid as component of the primary acylation pattern, was identified. In addition, the presence of a partially acylated phosphoglycerol moiety on the secondary acylation site at 3-position of the reducing GlcN caused a tremendous natural heterogeneity of the lipid A structure. Biological activity assays indicated that Colwellia psychrerythraea 34H lipid A did not show any either agonistic or antagonistic effect when tested in human macrophages. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| Germany | 1 | 25% |
| Italy | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 24 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 17% |
| Student > Ph. D. Student | 3 | 13% |
| Student > Postgraduate | 3 | 13% |
| Professor > Associate Professor | 3 | 13% |
| Student > Master | 2 | 8% |
| Other | 4 | 17% |
| Unknown | 5 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 5 | 21% |
| Chemistry | 4 | 17% |
| Agricultural and Biological Sciences | 4 | 17% |
| Business, Management and Accounting | 2 | 8% |
| Immunology and Microbiology | 2 | 8% |
| Other | 1 | 4% |
| Unknown | 6 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2017.
All research outputs
#15,509,219
of 24,578,676 outputs
Outputs from ChemBioChem
#3,427
of 5,916 outputs
Outputs of similar age
#182,503
of 321,490 outputs
Outputs of similar age from ChemBioChem
#44
of 106 outputs
Altmetric has tracked 24,578,676 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,916 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,490 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.