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The role of Enterococcus spp. and multidrug-resistant bacteria causing pyogenic liver abscesses

Overview of attention for article published in BMC Infectious Diseases, June 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
10 tweeters

Citations

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4 Dimensions

Readers on

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17 Mendeley
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Title
The role of Enterococcus spp. and multidrug-resistant bacteria causing pyogenic liver abscesses
Published in
BMC Infectious Diseases, June 2017
DOI 10.1186/s12879-017-2543-1
Pubmed ID
Authors

Marcus M. Mücke, Johanna Kessel, Victoria T. Mücke, Katharina Schwarzkopf, Michael Hogardt, Christoph Stephan, Stefan Zeuzem, Volkhard A. J. Kempf, Christian M. Lange

Abstract

Pyogenic liver abscesses (PLA) remain a significant clinical problem. Unfortunately, little is known about current bacterial susceptibility profiles and the incidence of multidrug resistant organisms (MDROs) causing PLA in Western countries. Yet, this crucial information is pivotal to guide empirical antibiotic therapy. Aim of this study was to provide detailed characteristics of PLA with a special focus on underlying bacterial pathogens and their susceptibility to antibiotics. A retrospective study of patients diagnosed with PLA from 2009 to 2015 in a large tertiary reference center in Germany was performed in order to characterize PLA and antimicrobial susceptibility profiles of causative bacterial species. Overall, 86 patients were included. The most common causes of PLA were bile duct stenosis/obstruction (31.4%) and leakage of biliary anastomosis (15.1%). Frequent predisposing diseases were malignancies (34.9%), diabetes (24.4%) and the presence of liver cirrhosis (16.3%). Of note, Enterococcus spp. were the most frequently cultured bacterial isolates (28.9%), and in 1/3 of cases vancomycin resistance was observed. In addition, a relevant frequency of gram-negative MDROs was identified. In particular, an alarming 10% and 20% of gram-negative bacteria were resistant to carbapenems and tigecycline, respectively. Of note, MDRO status did not predict ICU stay or survival in multivariate regression analysis. The mortality rate in our series was 16.3%. Our study demonstrates an as yet underreported role of Enterococcus spp., often associated with vancomycin resistance, as well as of gram-negative MDROs causing PLA.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 24%
Student > Doctoral Student 4 24%
Student > Postgraduate 3 18%
Student > Bachelor 2 12%
Researcher 2 12%
Other 2 12%
Readers by discipline Count As %
Medicine and Dentistry 11 65%
Biochemistry, Genetics and Molecular Biology 2 12%
Agricultural and Biological Sciences 1 6%
Immunology and Microbiology 1 6%
Unspecified 1 6%
Other 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2017.
All research outputs
#2,920,916
of 11,435,137 outputs
Outputs from BMC Infectious Diseases
#939
of 4,248 outputs
Outputs of similar age
#82,296
of 261,582 outputs
Outputs of similar age from BMC Infectious Diseases
#25
of 110 outputs
Altmetric has tracked 11,435,137 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,248 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,582 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.