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In vitro and cellular activities of the selected fruits residues for skin aging treatment

Overview of attention for article published in Anais da Academia Brasileira de Ciências, May 2017
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Title
In vitro and cellular activities of the selected fruits residues for skin aging treatment
Published in
Anais da Academia Brasileira de Ciências, May 2017
DOI 10.1590/0001-3765201720160849
Pubmed ID
Authors

Nattaya Lourith, Mayuree Kanlayavattanakul, Puxvadee Chaikul, Chaisak Chansriniyom, Pichaporn Bunwatcharaphansakun

Abstract

Peel extracts of litchi and rambutan, and that of tamarind seed coat were investigated in relation to their utility in skin-aging treatments. Standardized extracts of tamarind were significantly (p < 0.05) more efficient at O2 •- scavenging (IC50 = 27.44 ± 0.09) than those of litchi and rambutan (IC50 = 29.57 ± 0.30 and 39.49 ± 0.52 μg/ml, respectively) and the quercetin standard (IC50 = 31.88 ± 0.15 μg/ml). Litchi extract proved significantly (p < 0.05) more effective for elastase and collagenase inhibition (88.29 ± 0.25% and 79.46 ± 0.92%, respectively) than tamarind (35.43 ± 0.68% and 57.69 ± 5.97%) or rambutan (31.08 ± 0.38% and 53.99 ± 6.18%). All extracts were safe to human skin fibroblasts and inhibit MMP-2, with litchi extract showing significantly (p < 0.01) enhanced inhibition over the standard, vitamin C (23.75 ± 2.74% and 10.42 ± 5.91% at 0.05 mg/ml, respectively). Extracts suppress melanin production in B16F10 melanoma cells through inhibition of tyrosinase and TRP-2, with litchi extract being the most potent, even more so than kojic acid (standard). These results highlight the potential for adding value to agro-industrial waste, as the basis for the sustainable production of innovative, safe, anti-aging cosmetic products.

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Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 10%
Researcher 4 10%
Student > Bachelor 4 10%
Unspecified 3 7%
Lecturer 2 5%
Other 6 14%
Unknown 19 45%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 14%
Biochemistry, Genetics and Molecular Biology 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Unspecified 3 7%
Engineering 2 5%
Other 4 10%
Unknown 20 48%