Title |
Risk of anaphylaxis in opioid dependent persons: effects of heroin versus substitution substance
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Published in |
Substance Abuse Treatment, Prevention, and Policy, February 2014
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DOI | 10.1186/1747-597x-9-12 |
Pubmed ID | |
Authors |
Ute Maurer, Carola Kager, Christina Fellinger, Dagmara Loader, Augustin Pollesböck, Bernhard Spitzer, Reinhart Jarisch |
Abstract |
Across Europe, illicit drug-related mortality has not declined despite ever increasing prevention measures. The cause of these deaths has traditionally been associated with overdose. Previous findings have revealed the appearance of non-lethal opioid concentrations, leading us to investigate a further cause of death. The symptoms of heroin intoxication with asphyxia and/or cardiovascular involvement resemble anaphylaxis, and therefore it has been speculated that such deaths might be caused by an allergic reaction. The study´s aims were to investigate levels of allergic mediators in long-term injecting drug users (IDU) compared to healthy controls and to determine if oral opioid substitution therapy (OST) resulted in similar allergic symptoms to those reported by IDU after intravenous (IV) heroin use. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 4 | 57% |
Oman | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 100% |
Mendeley readers
Geographical breakdown
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United Kingdom | 1 | 2% |
United States | 1 | 2% |
Unknown | 47 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 9 | 18% |
Other | 5 | 10% |
Researcher | 5 | 10% |
Student > Doctoral Student | 5 | 10% |
Student > Bachelor | 3 | 6% |
Other | 10 | 20% |
Unknown | 12 | 24% |
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Medicine and Dentistry | 19 | 39% |
Agricultural and Biological Sciences | 4 | 8% |
Psychology | 3 | 6% |
Neuroscience | 3 | 6% |
Nursing and Health Professions | 2 | 4% |
Other | 6 | 12% |
Unknown | 12 | 24% |