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Caffeine Mediates Sustained Inactivation of Breast Cancer-Associated Myofibroblasts via Up-Regulation of Tumor Suppressor Genes

Overview of attention for article published in PLOS ONE, March 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

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101 X users
reddit
1 Redditor
video
1 YouTube creator

Citations

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34 Dimensions

Readers on

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54 Mendeley
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Title
Caffeine Mediates Sustained Inactivation of Breast Cancer-Associated Myofibroblasts via Up-Regulation of Tumor Suppressor Genes
Published in
PLOS ONE, March 2014
DOI 10.1371/journal.pone.0090907
Pubmed ID
Authors

Mysoon M. Al-Ansari, Abdelilah Aboussekhra

Abstract

Active cancer-associated fibroblasts (CAFs) or myofibroblasts play important roles not only in the development and progression of breast carcinomas, but also in their prognosis and treatment. Therefore, targeting these cells through suppressing their supportive procarcinogenic paracrine effects is mandatory for improving the current therapies that are mainly targeting tumor cells. To this end, we investigated the effect of the natural and pharmacologically safe molecule, caffeine, on CAF cells and their various procarcinogenic effects.

X Demographics

X Demographics

The data shown below were collected from the profiles of 101 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Spain 1 2%
Sri Lanka 1 2%
Unknown 51 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 19%
Student > Ph. D. Student 8 15%
Student > Bachelor 7 13%
Researcher 5 9%
Professor > Associate Professor 4 7%
Other 6 11%
Unknown 14 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 28%
Biochemistry, Genetics and Molecular Biology 10 19%
Medicine and Dentistry 7 13%
Chemistry 2 4%
Immunology and Microbiology 1 2%
Other 3 6%
Unknown 16 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 84. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2019.
All research outputs
#520,079
of 25,822,778 outputs
Outputs from PLOS ONE
#7,147
of 225,131 outputs
Outputs of similar age
#4,507
of 237,165 outputs
Outputs of similar age from PLOS ONE
#234
of 6,064 outputs
Altmetric has tracked 25,822,778 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 225,131 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,165 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 6,064 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.