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Mendeley readers
Attention Score in Context
| Title |
Lack of Social Support Raises Stress Vulnerability in Rats with a History of Ancestral Stress
|
|---|---|
| Published in |
Scientific Reports, July 2017
|
| DOI | 10.1038/s41598-017-05440-8 |
| Pubmed ID | |
| Authors |
Jamshid Faraji, Nabiollah Soltanpour, Hamid Lotfi, Reza Moeeini, Ali-Reza Moharreri, Shabnam Roudaki, S. Abedin Hosseini, David M. Olson, Ali-Akbar Abdollahi, Nasrin Soltanpour, Majid H. Mohajerani, Gerlinde A. S. Metz |
| Abstract |
Stress is a primary risk factor for psychiatric disorders. However, it is not fully understood why some stressed individuals are more vulnerable to psychiatric disorders than others. Here, we investigated whether multigenerational ancestral stress produces phenotypes that are sensitive to depression-like symptoms in rats. We also examined whether social isolation reveals potentially latent sensitivity to depression-like behaviours. F4 female rats born to a lineage of stressed mothers (F0-F3) received stress in adulthood while housed in pairs or alone. Social isolation during stress induced cognitive and psychomotor retardation only in rats exposed to ancestral stress. Social isolation also hampered the resilience of the hypothalamic-pituitary-adrenal axis to chronic stress and reduced hippocampal volume and brain-derived neurotrophic factor (BDNF) expression. Thus, synergy between social isolation and stress may unmask a latent history of ancestral stress, and raises vulnerability to mental health conditions. The findings support the notion that social support critically promotes stress coping and resilience. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Spain | 1 | 25% |
| Japan | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 15% |
| Student > Ph. D. Student | 7 | 13% |
| Student > Doctoral Student | 5 | 9% |
| Student > Postgraduate | 5 | 9% |
| Researcher | 5 | 9% |
| Other | 7 | 13% |
| Unknown | 16 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 9 | 17% |
| Medicine and Dentistry | 8 | 15% |
| Psychology | 5 | 9% |
| Biochemistry, Genetics and Molecular Biology | 3 | 6% |
| Engineering | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 17 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2017.
All research outputs
#14,355,715
of 22,988,380 outputs
Outputs from Scientific Reports
#68,059
of 124,114 outputs
Outputs of similar age
#174,377
of 312,390 outputs
Outputs of similar age from Scientific Reports
#2,765
of 5,407 outputs
Altmetric has tracked 22,988,380 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 124,114 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,390 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,407 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.