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Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System

Overview of attention for article published in PLOS ONE, March 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
83 X users
patent
3 patents
facebook
58 Facebook pages
wikipedia
3 Wikipedia pages
googleplus
7 Google+ users
reddit
1 Redditor

Citations

dimensions_citation
125 Dimensions

Readers on

mendeley
560 Mendeley
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Title
Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System
Published in
PLOS ONE, March 2014
DOI 10.1371/journal.pone.0089566
Pubmed ID
Authors

John M. McPartland, Geoffrey W. Guy, Vincenzo Di Marzo

Abstract

The "classic" endocannabinoid (eCB) system includes the cannabinoid receptors CB1 and CB2, the eCB ligands anandamide (AEA) and 2-arachidonoylglycerol (2-AG), and their metabolic enzymes. An emerging literature documents the "eCB deficiency syndrome" as an etiology in migraine, fibromyalgia, irritable bowel syndrome, psychological disorders, and other conditions. We performed a systematic review of clinical interventions that enhance the eCB system--ways to upregulate cannabinoid receptors, increase ligand synthesis, or inhibit ligand degradation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 83 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 560 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 <1%
Netherlands 2 <1%
Italy 1 <1%
Hungary 1 <1%
United Kingdom 1 <1%
Australia 1 <1%
Japan 1 <1%
Spain 1 <1%
Unknown 547 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 82 15%
Student > Bachelor 80 14%
Student > Ph. D. Student 64 11%
Student > Master 62 11%
Other 45 8%
Other 113 20%
Unknown 114 20%
Readers by discipline Count As %
Medicine and Dentistry 147 26%
Agricultural and Biological Sciences 48 9%
Pharmacology, Toxicology and Pharmaceutical Science 36 6%
Psychology 36 6%
Nursing and Health Professions 35 6%
Other 120 21%
Unknown 138 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 116. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2024.
All research outputs
#372,498
of 25,909,281 outputs
Outputs from PLOS ONE
#5,245
of 226,020 outputs
Outputs of similar age
#3,029
of 236,701 outputs
Outputs of similar age from PLOS ONE
#163
of 5,770 outputs
Altmetric has tracked 25,909,281 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 226,020 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,701 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 5,770 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.