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The Weber Effect and the United States Food and Drug Administration’s Adverse Event Reporting System (FAERS): Analysis of Sixty-Two Drugs Approved from 2006 to 2010

Overview of attention for article published in Drug Safety, March 2014
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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7 X users

Citations

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112 Dimensions

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106 Mendeley
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Title
The Weber Effect and the United States Food and Drug Administration’s Adverse Event Reporting System (FAERS): Analysis of Sixty-Two Drugs Approved from 2006 to 2010
Published in
Drug Safety, March 2014
DOI 10.1007/s40264-014-0150-2
Pubmed ID
Authors

Keith B. Hoffman, Mo Dimbil, Colin B. Erdman, Nicholas P. Tatonetti, Brian M. Overstreet

Abstract

The United States Food and Drug Administration's (FDA) Adverse Event Reporting System (FAERS) consists of adverse event (AE) reports linked to approved drugs. The database is widely used to support post-marketing safety surveillance programs. Sometimes cited as a limitation to the usefulness of FAERS, however, is the 'Weber effect,' which is often summarized by stating that AE reporting peaks at the end of the second year after a regulatory authority approves a drug. Weber described this effect in 1984 based upon a single class of medications prescribed in the United Kingdom. Since that time, the FDA has made a concerted effort to improve both reporting and the database itself. Both volume and quality of AE reporting has dramatically improved since Weber's report, with an estimated 800,000 yearly reports now being logged into FAERS.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 2%
Ireland 1 <1%
Finland 1 <1%
Israel 1 <1%
Denmark 1 <1%
Egypt 1 <1%
Unknown 99 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 21%
Researcher 15 14%
Student > Master 11 10%
Other 8 8%
Student > Bachelor 8 8%
Other 20 19%
Unknown 22 21%
Readers by discipline Count As %
Medicine and Dentistry 32 30%
Pharmacology, Toxicology and Pharmaceutical Science 17 16%
Computer Science 9 8%
Agricultural and Biological Sciences 5 5%
Nursing and Health Professions 3 3%
Other 11 10%
Unknown 29 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2022.
All research outputs
#6,370,575
of 23,508,125 outputs
Outputs from Drug Safety
#686
of 1,707 outputs
Outputs of similar age
#59,123
of 224,850 outputs
Outputs of similar age from Drug Safety
#8
of 20 outputs
Altmetric has tracked 23,508,125 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,707 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,850 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.