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Correlates of whole-blood polyunsaturated fatty acids among young children with moderate acute malnutrition

Overview of attention for article published in Nutrition Journal, July 2017
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Title
Correlates of whole-blood polyunsaturated fatty acids among young children with moderate acute malnutrition
Published in
Nutrition Journal, July 2017
DOI 10.1186/s12937-017-0264-3
Pubmed ID
Authors

C. W. Yaméogo, B. Cichon, C. Fabiansen, M. J. H. Rytter, D. Faurholt-Jepsen, K. D. Stark, A. Briend, S. Shepherd, A. S. Traoré, V. B. Christensen, K. F. Michaelsen, H. Friis, L. Lauritzen

Abstract

Severe acute malnutrition (SAM) has been associated with low polyunsaturated fatty acid (PUFA) status. However, investigations regarding PUFA status and correlates in children with moderate acute malnutrition (MAM) from low-income countries are scarce. The aim of this study was to describe whole-blood PUFA levels in children with moderate acute malnutrition (MAM) and to identify correlates of PUFAs. We conducted a cross-sectional study using baseline data from a prospective nutritional intervention trial among 1609 children with MAM aged 6-23 months in Burkina Faso,West Africa. Whole-blood PUFAs were measured by gas chromatography and expressed as percent of total whole-blood fatty acids (FA%). Potential correlates of PUFAs including infection, inflammation, hemoglobin, anthropometry (difference between children diagnosed as having MAM based on low mid-upper-arm-circumference (MUAC) only, low MUAC and weight-for-height z-score (WHZ), or low WHZ only) and diet were assessed by linear regression adjusted for age and sex. Children with MAM had low concentrations of whole-blood PUFAs, particularly n-3 PUFAs. Moreover, children diagnosed with MAM based only on low MUAC had 0.32 (95% confidence interval (CI), 0.14; 0.50) and 0.40 (95% CI, 0.16; 0.63) FA% lower arachidonic acid (AA) than those recruited based on both low WHZ as well as low MUAC and those recruited with low WHZ only, respectively. Infection and inflammation were associated with low levels of all long-chain (LC)-PUFAs, while hemoglobin was positively associated with whole-blood LC-PUFAs. While PUFA deficiency was not a general problem, overall whole-blood PUFA concentrations, especially of n-3 PUFAs, were low. Infection, inflammation, hemoglobin, anthropometry and diet were correlates of PUFAs concentrations in children with MAM. The trial is registered at http://www.isrctn.com ( ISRCTN42569496 ).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 14%
Researcher 10 12%
Student > Master 10 12%
Student > Ph. D. Student 8 9%
Student > Postgraduate 5 6%
Other 9 11%
Unknown 31 36%
Readers by discipline Count As %
Medicine and Dentistry 14 16%
Nursing and Health Professions 12 14%
Agricultural and Biological Sciences 6 7%
Social Sciences 6 7%
Economics, Econometrics and Finance 3 4%
Other 10 12%
Unknown 34 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 July 2017.
All research outputs
#7,477,538
of 22,988,380 outputs
Outputs from Nutrition Journal
#928
of 1,438 outputs
Outputs of similar age
#118,150
of 312,391 outputs
Outputs of similar age from Nutrition Journal
#9
of 15 outputs
Altmetric has tracked 22,988,380 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,438 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.2. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,391 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.