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Extraction conditions of white rose petals for the inhibition of enzymes related to skin aging

Overview of attention for article published in Laboratory Animal Research, October 2019
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Title
Extraction conditions of white rose petals for the inhibition of enzymes related to skin aging
Published in
Laboratory Animal Research, October 2019
DOI 10.5625/lar.2015.31.3.148
Pubmed ID
Authors

Ehn-Kyoung Choi, Haiyu Guo, Jae-Kwon Choi, Su-Kil Jang, Kyungha Shin, Ye-Seul Cha, Youngjin Choi, Da-Woom Seo, Yoon-Bok Lee, Seong-Soo Joo, Yun-Bae Kim

Abstract

In order to assess inhibitory potentials of white rose petal extracts (WRPE) on the activities of enzymes related to dermal aging according to the extraction conditions, three extraction methods were adopted. WRPE was prepared by extracting dried white rose (Rosa hybrida) petals with 50% ethanol (WRPE-EtOH), Pectinex® SMASH XXL enzyme (WRPE-enzyme) or high temperature-high pressure (WRPE-HTHP). In the inhibition of matrix metalloproteinase-1, although the enzyme activity was fully inhibited by all 3 extracts at 100 µg/mL in 60 min, partial inhibition (50-70%) was achieved only by WRPE-EtOH and WRPE-enzyme at 50 µg/mL. High concentrations (≥250 µg/mL) of all 3 extracts markedly inhibited the elastase activity. However, at low concentrations (15.6-125 µg/mL), only WRPE-EtOH inhibited the enzyme activity. Notably, WRPE-EtOH was superior to WRPE-enzyme and WRPE-HTHP in the inhibition of tyrosinase. WRPE-EtOH significantly inhibited the enzyme activity from 31.2 µM, reaching 80% inhibition at 125 µM. In addition to its strong antioxidative activity, the ethanol extract of white rose petals was confirmed to be effective in inhibiting skin aging-related enzymes. Therefore, it is suggested that WRPE-EtOH could be a good candidate for the improvement of skin aging such as wrinkle formation and pigmentation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 33%
Student > Postgraduate 1 8%
Student > Master 1 8%
Unknown 6 50%
Readers by discipline Count As %
Chemical Engineering 2 17%
Medicine and Dentistry 2 17%
Agricultural and Biological Sciences 1 8%
Veterinary Science and Veterinary Medicine 1 8%
Unknown 6 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2017.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Laboratory Animal Research
#116
of 149 outputs
Outputs of similar age
#319,669
of 372,378 outputs
Outputs of similar age from Laboratory Animal Research
#23
of 33 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 149 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.