@BeerninkPeter Per gen zijn tussen 7 en 8 TFB beschreven direct upstream. En Phantom beschrijft al 43000 enhancers: https://t.co/2DthTzSUpF ENCODE zelf bericht over meer dan 1,2 miljoen TFBs, om maar niet te spreken van de miljoenen epigenetische regulator
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@vitaliikl @jmschreiber91 @jhepkema @anshulkundaje @jeffvierstra @drklly @manusaraswat10 I'm sure you are already aware of the work from @albin_san and @carninci where empirically measured promoters and enhancers were then further defined by sequence and a
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@ChiragNepal @FANTOM_project Hi Chirag. Every sample was annotated with cell ontology or uberon anatomical ontology https://t.co/QAl1zRPKMY. @albin_san and @robin_andersson also reduced these down to 'facets' https://t.co/6wbgAZ1NOV
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.@Al__Forrest: Bi-directional CAGE signal above known enhancers (seen in https://t.co/BeLNKPILW2). Enhancers active in specific tissues showed overlap with SNPs significant in GWAS of diseases of that tissue. #genemappers19