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X Demographics
Mendeley readers
Attention Score in Context
| Title |
N-Linked Glycosylation of the p24 Family Protein p24δ5 Modulates Retrograde Golgi-to-ER Transport of K/HDEL Ligands in Arabidopsis
|
|---|---|
| Published in |
Molecular Plant, July 2017
|
| DOI | 10.1016/j.molp.2017.07.007 |
| Pubmed ID | |
| Authors |
Noelia Pastor-Cantizano, María Jesús García-Murria, Cesar Bernat-Silvestre, María Jesús Marcote, Ismael Mingarro, Fernando Aniento |
| Abstract |
The K/HDEL receptor ERD2 mediates the transport of soluble endoplasmic reticulum (ER) resident proteins containing a C-terminal K/HDEL signal from the Golgi apparatus back to the ER via COPI (COat Protein I)-coated vesicles. Sorting of ERD2 within COPI vesicles is facilitated by p24 proteins. In particular, Arabidopsis p24δ5 has been shown to interact directly with ERD2 (via its luminal GOLD -GOLgi Dynamics- domain) and with COPI proteins (via its cytoplasmic C-terminal tail) at the acidic pH of the Golgi apparatus. Several members of the p24 family in mammals and yeast have been shown to be glycosylated, but there was no previous report on glycosylation of Arabidopsis p24 proteins and on the role of the sugar moiety in p24 function. Here we show that the Arabidopsis p24 protein p24δ5 is N-glycosylated in its GOLD domain. In addition, we show that this post-translational modification is important for its coupled transport with p24β2 at the ER-Golgi interface, for its interaction with the K/HDEL receptor ERD2 and for retrograde transport of ERD2 and K/HDEL ligands from the Golgi apparatus back to the ER. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 3 | 43% |
| Spain | 1 | 14% |
| Germany | 1 | 14% |
| Unknown | 2 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 34% |
| Student > Master | 5 | 16% |
| Other | 2 | 6% |
| Student > Doctoral Student | 2 | 6% |
| Professor | 2 | 6% |
| Other | 3 | 9% |
| Unknown | 7 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 41% |
| Agricultural and Biological Sciences | 11 | 34% |
| Computer Science | 1 | 3% |
| Unknown | 7 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2017.
All research outputs
#7,716,445
of 25,382,440 outputs
Outputs from Molecular Plant
#794
of 1,758 outputs
Outputs of similar age
#112,361
of 325,062 outputs
Outputs of similar age from Molecular Plant
#17
of 29 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,758 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,062 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.