Title |
Comparison of the ACC/AHA and Framingham algorithms to assess cardiovascular risk in HIV-infected patients
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Published in |
Brazilian Journal of Infectious Diseases, July 2017
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DOI | 10.1016/j.bjid.2017.06.007 |
Pubmed ID | |
Authors |
Lauro Ferreira da Silva Pinto Neto, Fernanda Rezende Dias, Flavia Feres Bressan, Carolina Rocio Oliveira Santos |
Abstract |
The aim of this study was to compare the predictions of Framingham cardiovascular (CV) risk score (FRS) and the American College of Cardiology/American Heart Association (ACC/AHA) risk score in an HIV outpatient clinic in the city of Vitoria, Espirito Santo, Brazil. In a cross-sectional study 341 HIV infected patients over 40 years old consecutively recruited were interviewed. Cohen's kappa coefficient was used to assess agreement between the two algorithms. 61.3% were stratified as low risk by Framingham score, compared with 54% by ACC/AHA score (Spearman correlation 0.845; p<0.000). Only 26.1% were classified as CV high risk by Framingham compared to 46% by ACC/AHA score (Kappa=0.745; p<0.039). Only one out of eight patients had CV high risk by FRS at the time of a myocardial infarction event registered up to five years before the study period. Both CV risk scores but especially FRS underestimated CV high-risk patients in this HIV-infected population. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 61 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 11 | 18% |
Student > Postgraduate | 8 | 13% |
Student > Bachelor | 7 | 11% |
Researcher | 7 | 11% |
Student > Doctoral Student | 4 | 7% |
Other | 10 | 16% |
Unknown | 14 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 34% |
Nursing and Health Professions | 6 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Agricultural and Biological Sciences | 1 | 2% |
Other | 7 | 11% |
Unknown | 20 | 33% |